Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 16/20 | 0.43 |
| ▸ | HTR2A | P28223 | 4/20 | 0.43 |
| ▸ | HTR2C | P28335 | 4/20 | 0.43 |
| ▸ | HTR2B | P41595 | 4/20 | 0.43 |
| ▸ | NFATC1 | O95644 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5749097 | 0.85 | CNR2 (0.41) | HRH2HTR2AHTR2CHTR2BNFATC1 | |
| SCHEMBL4058347 | 0.84 | HRH2 (0.58) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL5750985 | 0.82 | HRH2 (0.53) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL4055816 | 0.81 | HRH2 (0.50) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL13768719 | 0.80 | HRH2 (0.58) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL5748984 | 0.79 | HRH2 (0.48) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL12975604 | 0.78 | APP (0.50) | HTR2CNFATC1GSK3BDYRK1A | |
| SCHEMBL4061658 | 0.78 | HTR2A (0.46) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL4060778 | 0.78 | HTR2A (0.43) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL4851778 | 0.74 | DYRK1A (0.50) | HRH2NFATC1GSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497292-B1 | AZAINDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | ALMIRALL PRODESFARMA SA (ES) | 2006-06-14 | — | — | EP | disclosed |
| EP-1497292-A1 | AZAINDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | Almirall Prodesfarma, S.A. (ES) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003082867-A1 | AZAINDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | ALMIRALL PRODESFARMA S.A. (ES) | 2003-10-09 | — | — | WO | disclosed |