Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 18/20 | 0.53 |
| ▸ | HTR2A | P28223 | 4/20 | 0.51 |
| ▸ | HTR2C | P28335 | 4/20 | 0.51 |
| ▸ | HTR2B | P41595 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4055816 | 0.91 | HRH2 (0.50) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL5748984 | 0.85 | HRH2 (0.48) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL5748447 | 0.82 | HRH2 (0.43) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL4053924 | 0.81 | HRH2 (0.81) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL4057910 | 0.80 | HRH2 (0.81) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL6157923 | 0.80 | HRH2 (0.47) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL4051922 | 0.80 | HRH2 (0.46) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL4053204 | 0.79 | HRH2 (0.80) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL4050360 | 0.78 | HRH2 (0.80) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL4055478 | 0.78 | HRH2 (0.66) | HRH2HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497292-B1 | AZAINDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | ALMIRALL PRODESFARMA SA (ES) | 2006-06-14 | — | — | EP | disclosed |