⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1307630 | 0.95 | CARM1 (0.50) | — | |
| SCHEMBL348038 | 0.93 | CARM1 (0.48) | — | |
| SCHEMBL1785086 | 0.84 | HDAC2 (0.41) | — | |
| SCHEMBL3951607 | 0.82 | SLC2A1 (0.37) | — | |
| SCHEMBL3949628 | 0.82 | ALDH1A1 (0.43) | — | |
| SCHEMBL1306925 | 0.82 | HRH3 (0.46) | — | |
| SCHEMBL3948277 | 0.82 | SLC2A1 (0.38) | — | |
| SCHEMBL3955882 | 0.80 | HSD17B10 (0.48) | — | |
| SCHEMBL272484 | 0.80 | KDM4E (0.47) | — | |
| SCHEMBL1781617 | 0.80 | HRH3 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020446-B1 | NAPHTHALIMIDOBENZAMIDE DERIVATIVES | TAIHO PHARMACEUTICAL CO LTD (JP) | 2006-03-15 | — | — | EP | disclosed |
| US-6300331-B1 | DRUGS AS ANTITUMOR AGENTS OR ANTICARCINOGENIC AGENTS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-1020446-A1 | NAPHTHALIMIDOBENZAMIDE DERIVATIVES | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2000-07-19 | — | — | EP | disclosed |