Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 11/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | BID | P55957 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5747890 | 1.00 | TLR8 (0.51) | TLR8PARP1LIPGKCNH2MAPT | |
| SCHEMBL5747569 | 1.00 | TLR8 (0.51) | TLR8PARP1LIPGKCNH2MAPT | |
| SCHEMBL5747159 | 0.95 | TLR8 (0.52) | TLR8PARP1LIPGKCNH2MAPT | |
| SCHEMBL5747866 | 0.95 | TLR8 (0.52) | TLR8PARP1LIPGKCNH2MAPT | |
| SCHEMBL5746387 | 0.95 | TLR8 (0.52) | TLR8PARP1LIPGKCNH2MAPT | |
| SCHEMBL10554489 | 0.91 | TLR8 (0.51) | TLR8LIPGKCNH2MAPTMTNR1A | |
| SCHEMBL1611673 | 0.84 | LIPG (0.50) | TLR8LIPGKCNH2MAPTMTNR1A | |
| SCHEMBL1610855 | 0.84 | LIPG (0.50) | TLR8LIPGKCNH2MAPTMTNR1A | |
| SCHEMBL1612051 | 0.84 | LIPG (0.50) | TLR8LIPGKCNH2MAPTMTNR1A | |
| SCHEMBL9394658 | 0.84 | LIPG (0.50) | TLR8LIPGKCNH2MAPTMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |