Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | TACR2 | P21452 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5748746 | 1.00 | PTGS2 (0.47) | PTGS2HTR2ACYP3A4KDM4EALDH1A1 | |
| SCHEMBL5750192 | 1.00 | PTGS2 (0.47) | PTGS2HTR2ACYP3A4KDM4EALDH1A1 | |
| SCHEMBL28315487 | 0.89 | PTGS2 (0.54) | PTGS2HTR2ACYP3A4KDM4EALDH1A1 | |
| SCHEMBL27083008 | 0.84 | PTGS2 (0.48) | PTGS2HTR2ACYP3A4KDM4EALDH1A1 | |
| SCHEMBL31066146 | 0.82 | HPGD (0.48) | PTGS2HTR2ACYP3A4KDM4EALDH1A1 | |
| SCHEMBL5747389 | 0.82 | SKP2 (0.41) | PTGS2HTR2ACYP3A4KDM4EALDH1A1 | |
| SCHEMBL5748540 | 0.82 | SKP2 (0.41) | PTGS2HTR2ACYP3A4KDM4EALDH1A1 | |
| SCHEMBL5749194 | 0.82 | SKP2 (0.41) | PTGS2HTR2ACYP3A4KDM4EALDH1A1 | |
| SCHEMBL15993628 | 0.81 | TDP1 (0.47) | PTGS2CYP3A4KDM4EALDH1A1HSD17B10 | |
| SCHEMBL5747729 | 0.81 | PTGS2 (0.46) | PTGS2HTR2ACYP3A4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |