Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | CTSV | O60911 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2258052 | 1.00 | MAPT (0.44) | MAPTKCNH2TLR8LIPGCTSV | |
| SCHEMBL2251595 | 1.00 | MAPT (0.44) | MAPTKCNH2TLR8LIPGCTSV | |
| SCHEMBL2253861 | 0.94 | MAPT (0.37) | MAPTKCNH2TLR8MEN1NPC1 | |
| SCHEMBL5750528 | 0.87 | KCNH2 (0.44) | MAPTKCNH2TLR8LIPGCTSV | |
| SCHEMBL2254077 | 0.87 | KCNH2 (0.44) | MAPTKCNH2TLR8LIPGCTSV | |
| SCHEMBL10760575 | 0.87 | KCNH2 (0.44) | MAPTKCNH2TLR8LIPGCTSV | |
| SCHEMBL292073 | 0.87 | KCNH2 (0.44) | MAPTKCNH2TLR8LIPGCTSV | |
| SCHEMBL11754126 | 0.87 | KCNH2 (0.44) | MAPTKCNH2TLR8LIPGCTSV | |
| SCHEMBL4629536 | 0.85 | KCNH2 (0.42) | MAPTKCNH2TLR8MEN1NPC1 | |
| SCHEMBL5024317 | 0.82 | GRIN2D (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |