Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2253861 | 0.84 | MAPT (0.37) | BCHE | |
| SCHEMBL2251595 | 0.82 | MAPT (0.44) | — | |
| SCHEMBL2258052 | 0.82 | MAPT (0.44) | — | |
| SCHEMBL5748802 | 0.82 | MAPT (0.44) | — | |
| SCHEMBL8176752 | 0.78 | ALDH1A1 (0.36) | ESR1 | |
| SCHEMBL5745901 | 0.77 | CYP1A2 (0.39) | — | |
| SCHEMBL2252836 | 0.71 | GAA (0.39) | — | |
| SCHEMBL4629536 | 0.70 | KCNH2 (0.42) | — | |
| SCHEMBL10760575 | 0.69 | KCNH2 (0.44) | — | |
| SCHEMBL292073 | 0.69 | KCNH2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1916244-A1 | THIOPHENE COMPOUND HAVING SULFONYL GROUP AND PROCESS FOR PRODUCING THE SAME | Nissan Chemical Industries, Ltd. (JP) | 2008-04-30 | — | — | EP | disclosed |