Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 6/20 | 0.46 |
| ▸ | GCKR | Q14397 | 7/20 | 0.44 |
| ▸ | F13A1 | P00488 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | TGM1 | P22735 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6356889 | 0.91 | CXCR3 (0.48) | CXCR3GCKRF13A1TGM2TGM1 | |
| SCHEMBL6357386 | 0.91 | CXCR3 (0.48) | CXCR3GCKRF13A1TGM2TGM1 | |
| SCHEMBL5480564 | 0.91 | CXCR3 (0.48) | CXCR3GCKRF13A1TGM2TGM1 | |
| SCHEMBL5748378 | 0.84 | GCKR (0.43) | GCKRF13A1TGM2TGM1KDM4E | |
| SCHEMBL6349119 | 0.84 | GCKR (0.43) | GCKRF13A1TGM2TGM1KDM4E | |
| SCHEMBL5797656 | 0.84 | GCKR (0.43) | GCKRF13A1TGM2TGM1KDM4E | |
| SCHEMBL5747281 | 0.84 | CXCR3 (0.45) | CXCR3F13A1TGM2TGM1KDM4E | |
| SCHEMBL6408554 | 0.83 | CXCR3 (0.48) | CXCR3GCKRF13A1TGM2TGM1 | |
| SCHEMBL5747924 | 0.83 | GCKR (0.43) | CXCR3GCKRF13A1TGM2TGM1 | |
| SCHEMBL5747872 | 0.82 | GCKR (0.45) | CXCR3GCKRF13A1TGM2TGM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1735280-A1 | ARYL SULFONAMIDE AND SULFONYL COMPOUNDS AS MODULATORS OF PPAR AND METHODS OF TREATING METABOLIC DISORDERS | Kalypsys, Inc. (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005115983-A1 | ARYL SULFONAMIDE AND SULFONYL COMPOUNDS AS MODULATORS OF PPAR AND METHODS OF TREATING METABOLIC DISORDERS | KALYPSYS, INC. (US) | 2005-12-08 | — | — | WO | disclosed |