Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27550187 | 1.00 | TDP1 (0.47) | TDP1L3MBTL1DHFRKCNH2PDPK1 | |
| SCHEMBL27524862 | 1.00 | TDP1 (0.47) | TDP1L3MBTL1DHFRKCNH2PDPK1 | |
| SCHEMBL5745538 | 1.00 | TDP1 (0.47) | TDP1L3MBTL1DHFRKCNH2PDPK1 | |
| SCHEMBL5746124 | 1.00 | TDP1 (0.47) | TDP1L3MBTL1DHFRKCNH2PDPK1 | |
| SCHEMBL5369216 | 0.98 | TDP1 (0.49) | TDP1L3MBTL1DHFRKCNH2PDPK1 | |
| SCHEMBL510211 | 0.93 | CYP2C9 (0.43) | TDP1L3MBTL1DHFRPDPK1HPGD | |
| Hydrochloric Acid SCHEMBL28992846 | 0.91 | CYP2C9 (0.42) | TDP1L3MBTL1PDPK1HPGDCYP1A2 | |
| SCHEMBL28506433 | 0.91 | CYP1A2 (0.41) | TDP1L3MBTL1DHFRKCNH2PDPK1 | |
| SCHEMBL29806076 | 0.85 | NOS2 (0.40) | L3MBTL1DHFRPDPK1HPGDCYP1A2 | |
| SCHEMBL1093436 | 0.85 | NOS2 (0.40) | L3MBTL1DHFRPDPK1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |