Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | RARB | P10826 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5750627 | 1.00 | RAB9A (0.53) | RAB9AMAPTKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL5748785 | 1.00 | RAB9A (0.53) | RAB9AMAPTKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL4563146 | 0.98 | RAB9A (0.50) | RAB9AMAPTKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL6615395 | 0.82 | NPC1 (0.41) | RAB9AMAPTKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL28055917 | 0.81 | RARB (0.50) | RAB9AMAPTKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL12186156 | 0.81 | RARB (0.50) | RAB9AMAPTKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL12186163 | 0.81 | RARB (0.50) | RAB9AMAPTKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL9850844 | 0.79 | MAPT (0.54) | RAB9AMAPTKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL8126315 | 0.79 | RARB (0.49) | RAB9AMAPTKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL7839207 | 0.79 | RARB (0.49) | RAB9AMAPTKDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |