SCHEMBL5749296

SCHEMBL5749296

NC(=O)c1c2ccccc2cc2ccccc12

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.65
KDM4E B2RXH2 4/20 0.65
KMT2A Q03164 4/20 0.65
MEN1 O00255 3/20 0.65
HSD17B10 Q99714 3/20 0.65
HPGD P15428 2/20 0.65
CYP2C19 P33261 2/20 0.65
CYP1A2 P05177 1/20 0.65
GLA P06280 1/20 0.65
GAA P10253 2/20 0.57
BCHE P06276 1/20 0.46
ACHE P22303 1/20 0.46
HTR2A P28223 1/20 0.45
HTT P42858 1/20 0.43
MAPT P10636 3/20 0.42
POLB P06746 2/20 0.42
PKM P14618 1/20 0.42
RAD52 P43351 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
CYP3A4 P08684 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27651681 0.98 ALDH1A1 (0.63) ALDH1A1KDM4EKMT2AMEN1HSD17B10
SCHEMBL30450396 0.90 ALDH1A1 (0.58) ALDH1A1KDM4EKMT2AMEN1HSD17B10
SCHEMBL5748916 0.87 ALDH1A1 (0.52) ALDH1A1KDM4EKMT2AMEN1HSD17B10
SCHEMBL5750421 0.87 ALDH1A1 (0.52) ALDH1A1KDM4EKMT2AMEN1HSD17B10
SCHEMBL25337557 0.86 KDM4E (0.55) ALDH1A1KDM4EKMT2AMEN1HSD17B10
SCHEMBL29588158 0.86 KDM4E (0.55) ALDH1A1KDM4EKMT2AMEN1HSD17B10
SCHEMBL5748330 0.84 KDM4E (0.49) ALDH1A1KDM4EKMT2AMEN1HSD17B10
SCHEMBL5749357 0.84 KDM4E (0.49) ALDH1A1KDM4EKMT2AMEN1HSD17B10
SCHEMBL3454685 0.84 KDM4E (0.52) ALDH1A1KDM4EKMT2AMEN1HSD17B10
SCHEMBL10499754 0.84 KDM4E (0.55) ALDH1A1KDM4EKMT2AMEN1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119039149-A Method for preparing aromatic methylamine 鞍山七彩化学股份有限公司 2024-11-29 CN disclosed
US-20240252674-A1 AGENTS FOR DIRECTED CONJUGATION TECHNIQUES AND CONJUGATED PRODUCTS BIOHAVEN THERAPEUTICS LTD. (VG) 2024-08-01 US disclosed
CN-116987045-A Heteroatom-containing substituted benzoxazinone derivative and preparation method and application thereof 中国医学科学院药物研究所 2023-11-03 CN disclosed
CN-116813979-A Nucleating agent, synthetic resin composition containing same, and molded article thereof 株式会社ADEKA 2023-09-29 CN disclosed
EP-3632443-B1 ANTI-TUMOR EFFECT POTENTIATOR USING A BIPHENYL COMPOUND TAIHO PHARMACEUTICAL CO LTD (JP) 2023-06-07 EP disclosed
CN-112839988-B Nucleating agent, synthetic resin composition containing same, and molded article thereof 株式会社ADEKA 2023-06-06 CN disclosed
CN-115768815-A Method for producing poly (anthranilamides), poly (anthranilamides) and use thereof 科思创德国股份有限公司 2023-03-07 CN disclosed
EP-3381896-B1 BIPHENYL COMPOUND OR SALT THEREOF TAIHO PHARMACEUTICAL CO LTD (JP) 2023-01-18 EP disclosed
US-20210179634-A1 NOVEL BIPHENYL COMPOUND OR SALT THEREOF TAIHO PHARMACEUTICAL CO., LTD. (JP) 2021-06-17 US disclosed
US-20210177826-A1 ANTI-TUMOR EFFECT POTENTIATOR USING NOVEL BIPHENYL COMPOUND TAIHO PHARMACEUTICAL CO., LTD. (JP) 2021-06-17 US disclosed
CN-1980910-A Benzopyran compound for treating arrhythmia NISSAN CHEMICAL IND LTD (JP) 2007-06-13 CN disclosed
US-7172867-B2 Methods of testing for allergic diseases, and therapeutic agents for treating same GENOX RESEARCH, INC. (JP) 2007-02-06 US disclosed
US-7172867-B2 Methods of testing for allergic diseases, and therapeutic agents for treating same GENOX RESEARCH, INC. (JP) 2007-02-06 US disclosed
US-7098245-B2 Polynucleotide cleavage agent switched on by photo irradiation TOTTORI UNIVERSITY (JP) 2006-08-29 US disclosed
EP-1020446-B1 NAPHTHALIMIDOBENZAMIDE DERIVATIVES TAIHO PHARMACEUTICAL CO LTD (JP) 2006-03-15 EP disclosed
US-20040058346-A1 Polynucleotide cleavage agent switched on by photo irradiation TOTTORI UNIVERSITY (JP) 2004-03-25 US disclosed
US-6300331-B1 DRUGS AS ANTITUMOR AGENTS OR ANTICARCINOGENIC AGENTS TAIHO PHARMACEUTICAL CO., LTD. (JP) 2001-10-09 US disclosed
EP-1020446-A1 NAPHTHALIMIDOBENZAMIDE DERIVATIVES TAIHO PHARMACEUTICAL CO., LTD. (JP) 2000-07-19 EP disclosed
US-4088772-A TRANQUILIZERS, ANALGESICS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-05-09 US disclosed
US-4076830-A TRANQUILIZERS, ANALGESICS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210177826-A1 ANTI-TUMOR EFFECT POTENTIATOR USING NOVEL BIPHENYL COMPOUND KDM1B, KDM1A, DOT1L ALDH1A1 538/4885KDM4E 24/4885KMT2A 15/4885
US-20240252674-A1 AGENTS FOR DIRECTED CONJUGATION TECHNIQUES AND CONJUGATED PRODUCTS CD47, EPHA2, CD2BP2 ALDH1A1 629/4885KDM4E 866/4885KMT2A 283/4885
US-20040058346-A1 Polynucleotide cleavage agent switched on by photo irradiation NSUN2, CPSF1, POLL ALDH1A1 3656/4885KDM4E 2798/4885KMT2A 1984/4885
US-20210179634-A1 NOVEL BIPHENYL COMPOUND OR SALT THEREOF KDM1B, KDM1A, HDAC1 ALDH1A1 416/4885KDM4E 23/4885KMT2A 14/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.