Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.57 |
| ▸ | EP300 | Q09472 | 1/20 | 0.55 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | FGB | P02675 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5746648 | 1.00 | IDO1 (0.57) | IDO1EP300KAT8ALDH1A1CYP3A4 | |
| SCHEMBL19999172 | 0.87 | NQO1 (0.50) | IDO1EP300KAT8ALDH1A1CYP3A4 | |
| SCHEMBL10392528 | 0.87 | NQO1 (0.50) | IDO1EP300KAT8ALDH1A1CYP3A4 | |
| SCHEMBL29876078 | 0.87 | NQO1 (0.50) | IDO1EP300KAT8ALDH1A1CYP3A4 | |
| SCHEMBL5746447 | 0.83 | IDO1 (0.47) | IDO1EP300KAT8ALDH1A1CYP3A4 | |
| SCHEMBL5746862 | 0.81 | NQO1 (0.42) | IDO1EP300KAT8ALDH1A1CYP3A4 | |
| SCHEMBL866016 | 0.80 | KEAP1 (0.42) | IDO1EP300KAT8ALDH1A1CYP3A4 | |
| SCHEMBL29372072 | 0.80 | KEAP1 (0.42) | IDO1EP300KAT8ALDH1A1CYP3A4 | |
| SCHEMBL867279 | 0.80 | KEAP1 (0.42) | IDO1EP300KAT8ALDH1A1CYP3A4 | |
| SCHEMBL2351815 | 0.79 | HPGD (0.54) | IDO1ALDH1A1CYP3A4TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |