SCHEMBL574956

SCHEMBL574956

N=CC=Cc1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.68
MAPK1 P28482 2/20 0.56
ALDH1A1 P00352 2/20 0.56
LMNA P02545 2/20 0.56
TRPA1 O75762 1/20 0.56
ALOX5 P09917 1/20 0.56
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
MAPT P10636 2/20 0.46
RECQL P46063 2/20 0.46
POLB P06746 1/20 0.46
CMA1 P23946 1/20 0.45
NFE2L2 Q16236 1/20 0.44
CYP19A1 P11511 1/20 0.44
MAOA P21397 1/20 0.44
HDAC3 O15379 2/20 0.43
HDAC4 P56524 2/20 0.43
HDAC1 Q13547 2/20 0.43
HDAC7 Q8WUI4 2/20 0.43
HDAC2 Q92769 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6407522 1.00 MAOB (0.68) MAOBMAPK1ALDH1A1LMNATRPA1
SCHEMBL12992717 1.00 MAOB (0.68) MAOBMAPK1ALDH1A1LMNATRPA1
SCHEMBL19956847 0.90 MAOB (0.70) MAOBMAPK1ALDH1A1LMNATRPA1
Benzene SCHEMBL135524 0.82 MAOB (1.00) MAOBMAPK1ALDH1A1LMNATRPA1
SCHEMBL5875512 0.82 MAOB (1.00) MAOBMAPK1ALDH1A1LMNATRPA1
SCHEMBL23458007 0.82 MAOB (1.00) MAOBMAPK1ALDH1A1LMNATRPA1
SCHEMBL592744 0.82 MAOB (1.00) MAOBMAPK1ALDH1A1LMNATRPA1
Benzene SCHEMBL9803304 0.82 MAOB (1.00) MAOBMAPK1ALDH1A1LMNATRPA1
SCHEMBL6853572 0.82 MAOB (1.00) MAOBMAPK1ALDH1A1LMNATRPA1
SCHEMBL718317 0.82 MAOB (1.00) MAOBMAPK1ALDH1A1LMNATRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11091608-B2 Elastomeric composition and vulcanization accelerator used therein PIRELLI TYRE S.P.A. (IT) 2021-08-17 US disclosed
EP-3397678-B1 ELASTOMERIC COMPOSITION AND VULCANIZATION ACCELERATOR USED THEREIN PIRELLI (IT) 2021-07-28 EP disclosed
US-20210179821-A1 ELASTOMERIC COMPOSITION AND VULCANIZATION ACCELERATOR USED THEREIN PIRELLI TYRE S.P.A. (IT) 2021-06-17 US disclosed
CN-108463499-B Elastomer composition and vulcanization accelerator used therein 倍耐力轮胎股份公司 2020-03-10 CN disclosed
EP-3397678-A1 ELASTOMERIC COMPOSITION AND VULCANIZATION ACCELERATOR USED THEREIN Pirelli Tyre S.p.A. (IT) 2018-11-07 EP disclosed
WO-2017115253-A1 ELASTOMERIC COMPOSITION AND VULCANIZATION ACCELERATOR USED THEREIN PIRELLI TYRE S.P.A. (IT) 2017-07-06 WO disclosed
US-9399652-B2 Synthetic route to pactamycin and pactamycin analogs THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2016-07-26 US disclosed
US-20150329570-A1 SYNTHETIC ROUTE TO PACTAMYCIN AND PACTAMYCIN ANALOGS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2015-11-19 US disclosed
US-8759007-B2 Method to produce a receptor chip using biotinylated protein NATIONAL FOOD RESEARCH INSTITUTE (JP) 2014-06-24 US disclosed
US-8318085-B2 Methods and compositions for inhibiting metal corrosion HALLIBURTON ENERGY SERVICES, INC. (US) 2012-11-27 US disclosed
EP-1689911-A1 METHODS AND COMPOSITIONS FOR INHIBITING METAL CORROSION Halliburton Energy Services, Inc. (US) 2006-08-16 EP disclosed
WO-2005054544-A1 METHODS AND COMPOSITIONS FOR INHIBITING METAL CORROSION HALLIBURTON ENERGY SERVICES, INC. (US) 2005-06-16 WO disclosed
US-20050123437-A1 Methods and compositions for inhibiting metal corrosion HALLIBURTON ENERGY SERVICES, INC. 2005-06-09 US disclosed
US-20040209294-A1 Method to produce a receptor chip using biotinylated protein NATIONAL FOOD RESEARCH INSTITUTE (JP) 2004-10-21 US disclosed
US-5426143-A Optical data storage films containing non-liquid crystalline polymer and infrared-activated dye either mixed with or covalently bonded to polymer AKZO NOBEL N.V. (NL) 1995-06-20 US disclosed
EP-0608019-A1 Thermochromic infrared dyes Akzo Nobel N.V. (NL) 1994-07-27 EP disclosed
US-4196291-A ANTHELMINTICS MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1980-04-01 US disclosed
US-4141978-A ANTHELMINTICS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1979-02-27 US disclosed
US-4113867-A ANTHELMINTICS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1978-09-12 US disclosed
US-4001411-A ANTHELMINTICS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150329570-A1 SYNTHETIC ROUTE TO PACTAMYCIN AND PACTAMYCIN ANALOGS PAICS, DPM1, MANBA MAOB 1503/4885MAPK1 1124/4885ALDH1A1 1424/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.