SCHEMBL6407522

SCHEMBL6407522

N=C/C=C/c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.68
MAPK1 P28482 2/20 0.56
ALDH1A1 P00352 2/20 0.56
LMNA P02545 2/20 0.56
TRPA1 O75762 1/20 0.56
ALOX5 P09917 1/20 0.56
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
MAPT P10636 2/20 0.46
RECQL P46063 2/20 0.46
POLB P06746 1/20 0.46
CMA1 P23946 1/20 0.45
NFE2L2 Q16236 1/20 0.44
CYP19A1 P11511 1/20 0.44
MAOA P21397 1/20 0.44
HDAC3 O15379 2/20 0.43
HDAC4 P56524 2/20 0.43
HDAC1 Q13547 2/20 0.43
HDAC7 Q8WUI4 2/20 0.43
HDAC2 Q92769 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL574956 1.00 MAOB (0.68) MAOBMAPK1ALDH1A1LMNATRPA1
SCHEMBL12992717 1.00 MAOB (0.68) MAOBMAPK1ALDH1A1LMNATRPA1
SCHEMBL19956847 0.90 MAOB (0.70) MAOBMAPK1ALDH1A1LMNATRPA1
Benzene SCHEMBL135524 0.82 MAOB (1.00) MAOBMAPK1ALDH1A1LMNATRPA1
SCHEMBL5875512 0.82 MAOB (1.00) MAOBMAPK1ALDH1A1LMNATRPA1
SCHEMBL23458007 0.82 MAOB (1.00) MAOBMAPK1ALDH1A1LMNATRPA1
SCHEMBL592744 0.82 MAOB (1.00) MAOBMAPK1ALDH1A1LMNATRPA1
Benzene SCHEMBL9803304 0.82 MAOB (1.00) MAOBMAPK1ALDH1A1LMNATRPA1
SCHEMBL6853572 0.82 MAOB (1.00) MAOBMAPK1ALDH1A1LMNATRPA1
SCHEMBL718317 0.82 MAOB (1.00) MAOBMAPK1ALDH1A1LMNATRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1537853-A1 Use of a composition comprising a compound comprising a lacton ring and/or a corresponding coloring agent with an open ring for dyeing keratinuous fibers L'OREAL (FR) 2005-06-08 EP claimed
US-20230276693-A1 LIGHT-EMITTING DEVICE, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND MIXTURE SAMSUNG DISPLAY CO., LTD. (KR) 2023-08-31 US disclosed
US-20230048387-A1 CORROSION PROTECTION METHOD FOR WELLBORE PIPING KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2023-02-16 US disclosed
US-20190084941-A1 COMPOUNDS AND METHODS OF TREATING INFECTIONS NEOCULI PTY LTD (AU) 2019-03-21 US disclosed
US-7244851-B2 1-[2-Cyclohexyl-2-(2-methylamino-propionylamino)-acetyl]-pyrrolidine-2-carboxylic acid (2-phenyl-2H-pyrazol-3-yl)-amide; inhibitors of IAP, for treating malignancies GENENTECH, INC. (US) 2007-07-17 US disclosed
EP-1537853-A1 Use of a composition comprising a compound comprising a lacton ring and/or a corresponding coloring agent with an open ring for dyeing keratinuous fibers L'OREAL (FR) 2005-06-08 EP disclosed
WO-2001098313-A1 CARBON DIOXIDE SEQUESTRATION BY COBALT (II) COMPLEXES LATTICE INTELLECTUAL PROPERTY LTD (GB) 2001-12-27 WO disclosed
CN-1295071-A Condensed imidezo-[1,2-a] pyridines NEW JAPAN MEDICINE CO LTD (JP) 2001-05-16 CN disclosed
CN-1064360-C Fused imidazo [1, 2-a ] pyridines SHINIPPON PHARMACEUTICAL INC (JP) 2001-04-11 CN disclosed
US-6103736-A SHOWING AN INHIBITORY ACTION ON GASTRIC ACID SECRETION AND A PROTECTIVE ACTION OF GASTRIC MUCOSA; 2-(HETERO)ARYL-3-AMINOIMIDAZO-(2,1-A)ISOQUINOLINES; ANTIULCER AGENTS; SHINNIPPON PHARMACEUTICAL INC. (JP) 2000-08-15 US disclosed
US-6020342-A Fused imidazo[1,2-A]pyridines SHINNIPPON PHARMACEUTICAL, INC. (JP) 2000-02-01 US disclosed
CN-1182428-A Fused imidazo [1, 2-alpha ] pyridines SHINNIPPON PHARMACEUTICAL INC (JP) 1998-05-20 CN disclosed
EP-0822194-A1 FUSED IMIDAZO 1,2-a]PYRIDINES Shinnippon Pharmaceutical Inc. (JP) 1998-02-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190084941-A1 COMPOUNDS AND METHODS OF TREATING INFECTIONS ELANE, IL1A, IL1B MAOB 641/4885MAPK1 1453/4885ALDH1A1 1016/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.