Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1556062 | 0.82 | NCEH1 (0.45) | CYP1A2CYP2A6ALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL19433082 | 0.82 | TLR8 (0.50) | ALDH1A1HSD17B10CYP3A4ALOX15CASP1 | |
| SCHEMBL5747084 | 0.80 | TLR8 (0.49) | ALDH1A1HSD17B10CYP3A4ALOX15CASP1 | |
| SCHEMBL5751347 | 0.80 | TLR8 (0.49) | ALDH1A1HSD17B10CYP3A4ALOX15CASP1 | |
| SCHEMBL5748674 | 0.80 | TLR8 (0.49) | ALDH1A1HSD17B10CYP3A4ALOX15CASP1 | |
| SCHEMBL9137780 | 0.79 | CYP1A2 (0.44) | CYP1A2CYP2A6ALDH1A1HSD17B10HIF1A | |
| SCHEMBL27677260 | 0.78 | CYP1A2 (0.42) | CYP1A2CYP2A6ALDH1A1HSD17B10HIF1A | |
| SCHEMBL10984867 | 0.78 | CYP2A6 (0.48) | CYP1A2CYP2A6ALDH1A1HSD17B10HIF1A | |
| SCHEMBL28242289 | 0.77 | ALDH1A1 (0.37) | ALDH1A1HSD17B10HIF1ACYP3A4ALOX15 | |
| SCHEMBL498622 | 0.76 | ALDH1A1 (0.46) | CYP1A2CYP2A6ALDH1A1HSD17B10HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |