Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | TACR2 | P21452 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5747292 | 1.00 | TLR8 (0.48) | TLR8S1PR4S1PR1S1PR5ESR1 | |
| SCHEMBL5746267 | 1.00 | TLR8 (0.48) | TLR8S1PR4S1PR1S1PR5ESR1 | |
| SCHEMBL5746960 | 0.88 | TLR8 (0.48) | TLR8S1PR4S1PR1S1PR5ESR1 | |
| SCHEMBL5747842 | 0.88 | TLR8 (0.48) | TLR8S1PR4S1PR1S1PR5ESR1 | |
| SCHEMBL5747288 | 0.88 | TLR8 (0.48) | TLR8S1PR4S1PR1S1PR5ESR1 | |
| SCHEMBL28065707 | 0.78 | TLR8 (0.53) | TLR8S1PR4S1PR1S1PR5ESR1 | |
| SCHEMBL6289604 | 0.76 | TLR8 (0.55) | TLR8S1PR4S1PR1S1PR5ESR1 | |
| SCHEMBL6290855 | 0.74 | TLR8 (0.54) | TLR8S1PR4S1PR1S1PR5ESR1 | |
| SCHEMBL11690859 | 0.74 | PTGS2 (0.57) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL11222681 | 0.74 | PTGS2 (0.57) | ESR1ADRA2AADORA3TACR2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |