SCHEMBL57500

SCHEMBL57500

CCOC(CCCl)OCC

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.40
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21049743 0.97 THRB (0.38) THRBLMNA
Ether SCHEMBL21049752 0.90 THRB (0.33) THRBLMNA
SCHEMBL432588 0.83 TSHR (0.36) THRBLMNA
Hydrochloric Acid SCHEMBL11270295 0.83 THRB (0.32) THRBLMNA
SCHEMBL10761201 0.81 TSHR (0.38) THRBLMNA
SCHEMBL5666168 0.81 THRB (0.50) THRBLMNA
SCHEMBL21484039 0.79 TSHR (0.42) THRBLMNA
SCHEMBL11482621 0.79 TSHR (0.42) THRBLMNA
SCHEMBL21484054 0.79 TSHR (0.42) THRBLMNA
SCHEMBL21484048 0.79 TSHR (0.42) THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 268 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0582506-B1 Tetrahydronaphtalene derivatives, their preparation and their application in therapy SYNTHELABO (FR) 1996-02-28 EP claimed
EP-0582506-A1 Tetrahydronaphtalene derivatives, their preparation and their application in therapy SYNTHELABO (FR) 1994-02-09 EP claimed
US-4847403-A 2-Isopropyl-2-(2-methylphenyl)-5-(N-methyl-N-homoveratrylamino)-valeronitrile and method for producing same SPOFA, SPOJENE PODNIKY PRO ZDRAVOTNICKOU (CS) 1989-07-11 US claimed
EP-0257768-A1 2-Isopropyl-2-phenyl-5-(N-methyl-2-phenylethylamino)-valeronitrile derivatives and processes for their preparation SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu (CS) 1988-03-02 EP claimed
JP-6172282-A None JP disclosed
CN-224194706-U Synthesis device of 3-chloropropionaldehyde diethyl acetal 杭州柏榆生物科技有限公司 2026-05-05 CN disclosed
CN-224194706-U Synthesis device of 3-chloropropionaldehyde diethyl acetal 杭州柏榆生物科技有限公司 2026-05-05 CN disclosed
EP-4644377-A1 LIPID COMPOUND FOR GENE DELIVERY AND LIPID NANOPARTICLE COMPRISING SAME NANJING CYBERNAX BIOMEDICAL TECHNOLOGY CO., LTD. (CN) 2025-11-05 EP disclosed
EP-3227271-B1 HETEROCYCLIC DERIVATIVES AND USE THEREOF C&C RES LAB (KR) 2025-08-13 EP disclosed
WO-2025120550-A1 INTERMEDIATE COMPOUND USED IN PREPARING HETEROCYCLE DERIVATIVE, METHOD FOR PREPARING INTERMEDIATE COMPOUND, AND METHOD FOR PREPARING HETEROCYCLE DERIVATIVE USING SAME 제이더블유중외제약 주식회사 2025-06-12 WO disclosed
WO-2025120551-A1 INTERMEDIATE COMPOUND USED IN PREPARING HETEROCYCLE DERIVATIVE, METHOD FOR PREPARING SAME, AND METHOD FOR PREPARING HETEROCYCLE DERIVATIVE USING SAME 제이더블유중외제약 주식회사 2025-06-12 WO disclosed
CN-115557991-B Preparation method and application of 3, 3-dialkoxyl propyl methyl phosphonate 中国药科大学 2025-04-18 CN disclosed
US-4179510-A ISOCHROMANS AND 2-BENZOXEPINS THE UPJOHN COMPANY (US) 1979-12-18 US disclosed
US-4174210-A Herbicidal and plant-growth regulating N-haloacetylphenylamino carbonyl oximes CHEVRON RESEARCH COMPANY (US) 1979-11-13 US disclosed
US-4166062-A HYPOTENSIVE AGENTS, CNS, ANTIDEPRESSANTS THE UPJOHN COMPANY (US) 1979-08-28 US disclosed
US-4163112-A INSECTICIDES VELSICOL CHEMICAL CORPORATION (US) 1979-07-31 US disclosed
US-4153612-A 2-Benzoxepins THE UPJOHN COMPANY (US) 1979-05-08 US disclosed
US-4066648-A ANTIDEPRESSANTS, ANALGESICS, DIURETICS, ANTIINFLAMMATORY AGENTS, MUSCLE RELAXANTS, VASODIALATORS, HYPOTENSIVE AGENTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1978-01-03 US disclosed
US-4054652-A ENZYME INHIBITORS MERCK & CO., INC. (US) 1977-10-18 US disclosed
US-4025625-A INHIBITORS OF THE ENZYME INDOLEAMINE-N-METHYL TRANSFERASE MERCK & CO., INC. (US) 1977-05-24 US disclosed