N-Phenyl-Phthalimide

N-Phenyl-Phthalimide

SCHEMBL575012

O=C1c2ccccc2C(=O)N1c1ccccc1.c1ccc(-c2cc[nH]n2)cc1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.46
SCN2A Q99250 3/20 0.44
CA12 O43570 2/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA9 Q16790 2/20 0.44
HTT P42858 1/20 0.44
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
HSPA1A P0DMV8 1/20 0.43
PABPC1 P11940 1/20 0.43
ESR1 P03372 1/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
CASP1 P29466 1/20 0.43
CASP3 P42574 1/20 0.43
CASP7 P55210 1/20 0.43
SENP8 Q96LD8 1/20 0.43
HSD17B10 Q99714 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9438 0.78 CYP1A2 (0.48) KMT2AMEN1ALDH1A1HPGDCYP1A2
SCHEMBL514705 0.76 CYP1A2 (0.47) KMT2AMEN1ALDH1A1HPGDCYP1A2
Phosphine SCHEMBL28114703 0.76 CYP1A2 (0.47) KMT2AMEN1ALDH1A1HPGDCYP1A2
SCHEMBL31519384 0.76 CYP1A2 (0.47) KMT2AMEN1ALDH1A1HPGDCYP1A2
SCHEMBL30636164 0.76 CYP1A2 (0.47) KMT2AMEN1ALDH1A1HPGDCYP1A2
SCHEMBL842040 0.76 CYP1A2 (0.47) KMT2AMEN1ALDH1A1HPGDCYP1A2
Ammonia Solution, Strong SCHEMBL29843017 0.76 CYP1A2 (0.47) KMT2AMEN1ALDH1A1HPGDCYP1A2
SCHEMBL28309054 0.76 CYP1A2 (0.47) KMT2AMEN1ALDH1A1HPGDCYP1A2
N-Phenyl-Phthalimide SCHEMBL123618 0.76 KMT2A (0.68) SCN2ACA12CA1CA2CA9
SCHEMBL19773976 0.76 KMT2A (0.68) SCN2ACA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11111500-B2 Mutated protoporphyrinogen IX oxidase (PPX) genes CIBUS US LLC (US) 2021-09-07 US disclosed
EP-3441469-A1 MUTATED PROTOPORPHYRINOGEN IX OXIDASE (PPX) GENES Cibus US LLC (US) 2019-02-13 EP disclosed
US-20180327773-A1 MUTATED PROTOPORPHYRINOGEN IX OXIDASE (PPX) GENES CIBUS US LLC (US) 2018-11-15 US disclosed
EP-2600710-B1 MUTATED PROTOPORPHYRINOGEN IX OXIDASE (PPX) GENES CIBUS US LLC (US) 2018-08-01 EP disclosed
US-20140189906-A1 MUTATED PROTOPORPHYRINOGEN IX OXIDASE (PPX) GENES CIBUS EUROPE BV (NL) 2014-07-03 US disclosed
EP-2600710-A2 MUTATED PROTOPORPHYRINOGEN IX OXIDASE (PPX) GENES Cibus US LLC (US) 2013-06-12 EP disclosed
US-20120122223-A1 MUTATED PROTOPORPHYRINOGEN IX OXIDASE (PPX) GENES CIBUS US LLC 2012-05-17 US disclosed
WO-2012018862-A2 MUTATED PROTOPORPHYRINOGEN IX OXIDASE (PPX) GENES CIBUS US LLC (US) 2012-02-09 WO disclosed