SCHEMBL5750176

SCHEMBL5750176

Nc1ccc2cc3cc(C=O)ccc3cc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.56
CYP3A4 P08684 3/20 0.56
HSD17B10 Q99714 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
ALOX15 P16050 1/20 0.56
CASP1 P29466 1/20 0.56
CASP7 P55210 1/20 0.56
HBB P68871 1/20 0.56
HIF1A Q16665 1/20 0.56
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
KDM4E B2RXH2 2/20 0.43
MAPT P10636 1/20 0.43
CYP2A6 P11509 6/20 0.41
F2 P00734 1/20 0.40
LMNA P02545 1/20 0.40
CHRM2 P08172 1/20 0.40
HTR1A P08908 1/20 0.40
ADRA2A P08913 1/20 0.40
ADORA3 P0DMS8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5748061 1.00 ALDH1A1 (0.56) ALDH1A1CYP3A4HSD17B10TDP1ALOX15
SCHEMBL2346924 0.96 ALDH1A1 (0.50) ALDH1A1CYP3A4HSD17B10TDP1ALOX15
SCHEMBL29957342 0.96 ALDH1A1 (0.50) ALDH1A1CYP3A4HSD17B10TDP1ALOX15
SCHEMBL9099739 0.94 ALDH1A1 (0.48) ALDH1A1CYP3A4HSD17B10TDP1ALOX15
SCHEMBL29954379 0.94 ALDH1A1 (0.48) ALDH1A1CYP3A4HSD17B10TDP1ALOX15
SCHEMBL19182196 0.87 CYP2A6 (0.50) ALDH1A1HSD17B10TDP1KDM4ECYP2A6
SCHEMBL9883838 0.87 CYP2A6 (0.50) ALDH1A1HSD17B10TDP1KDM4ECYP2A6
SCHEMBL30972495 0.87 CYP2A6 (0.50) ALDH1A1HSD17B10TDP1KDM4ECYP2A6
SCHEMBL29617405 0.87 CYP2A6 (0.50) ALDH1A1HSD17B10TDP1KDM4ECYP2A6
SCHEMBL29617404 0.87 CYP2A6 (0.50) ALDH1A1HSD17B10TDP1KDM4ECYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190169671-A1 Methods for Detecting Mycobacteria with Solvatochromic Dye Conjugates THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2019-06-06 US disclosed
US-20060293503-A1 Polyaminopyridines and method for producing same SUMITOMO SEIKA CHEMICALS CO., LTD (JP) 2006-12-28 US disclosed
EP-1669390-A1 POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2006-06-14 EP disclosed