Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5746640 | 1.00 | TLR7 (0.48) | TLR7LMNASMN1; SMN2S1PR2NPSR1 | |
| SCHEMBL5750193 | 1.00 | TLR7 (0.48) | TLR7LMNASMN1; SMN2S1PR2NPSR1 | |
| SCHEMBL294604 | 0.87 | KDM4E (0.46) | TLR7LMNASMN1; SMN2S1PR2NPSR1 | |
| SCHEMBL5748561 | 0.80 | MEN1 (0.36) | TLR7LMNASMN1; SMN2S1PR2NPSR1 | |
| SCHEMBL10585446 | 0.72 | LOXL2 (0.53) | TLR7LMNASMN1; SMN2S1PR2NPSR1 | |
| SCHEMBL6115140 | 0.72 | LOXL2 (0.53) | TLR7LMNASMN1; SMN2S1PR2NPSR1 | |
| SCHEMBL6114811 | 0.72 | LOXL2 (0.53) | TLR7LMNASMN1; SMN2S1PR2NPSR1 | |
| SCHEMBL6114551 | 0.72 | LOXL2 (0.53) | TLR7LMNASMN1; SMN2S1PR2NPSR1 | |
| SCHEMBL6114968 | 0.72 | LOXL2 (0.53) | TLR7LMNASMN1; SMN2S1PR2NPSR1 | |
| SCHEMBL6115139 | 0.72 | LOXL2 (0.53) | TLR7LMNASMN1; SMN2S1PR2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |