Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | CCR1 | P32246 | 2/20 | 0.31 |
| ▸ | CTSV | O60911 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5754762 | 0.92 | DGAT2 (0.36) | DGAT2MAPTP2RX7THRBBACE1 | |
| SCHEMBL5752859 | 0.89 | BACE1 (0.34) | DGAT2BACE1CTSLCTSBCTSS | |
| SCHEMBL5753487 | 0.86 | MAPT (0.36) | DGAT2MAPTP2RX7THRBBACE1 | |
| SCHEMBL5750976 | 0.85 | CETP (0.38) | DGAT2MAPTP2RX7THRBBACE1 | |
| SCHEMBL5751322 | 0.81 | ITGB1 (0.41) | DGAT2MAPTP2RX7 | |
| SCHEMBL5749361 | 0.81 | BACE1 (0.34) | DGAT2BACE1CTSLCTSBCTSS | |
| SCHEMBL5754301 | 0.79 | ITGB1 (0.38) | DGAT2MAPTP2RX7THRBBACE1 | |
| SCHEMBL5749779 | 0.76 | CETP (0.40) | BACE1 | |
| SCHEMBL5753763 | 0.76 | MCHR1 (0.40) | DGAT2P2RX7 | |
| SCHEMBL5751747 | 0.75 | MCHR1 (0.34) | DGAT2BACE1CTSVCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6982348-B2 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-01-03 | — | — | US | disclosed |
| US-20040127574-A1 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-07-01 | — | — | US | disclosed |
| EP-1362846-A1 | AMINOETHANOL DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2003-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127574-A1 | Aminoethanol derivatives | CETP, LCAT, MTTP | DGAT2 206/4885MAPT 2688/4885P2RX7 4828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.