Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5749223 | 0.94 | PARP1 (0.46) | PARP1ALDH1A1HPGDCYP3A4TSHR | |
| SCHEMBL498622 | 0.82 | ALDH1A1 (0.46) | ALDH1A1HSD17B10KDM4EGAAMAPT | |
| SCHEMBL13716722 | 0.81 | PARP1 (0.45) | PARP1ALDH1A1HPGDCYP3A4TSHR | |
| SCHEMBL29351158 | 0.81 | ALDH1A1 (0.62) | ALDH1A1HPGDCYP3A4TSHRHSD17B10 | |
| SCHEMBL5545202 | 0.81 | ALDH1A1 (0.62) | ALDH1A1HPGDCYP3A4TSHRHSD17B10 | |
| SCHEMBL31158567 | 0.80 | ALDH1A1 (0.44) | ALDH1A1HSD17B10KDM4EGAAMAPT | |
| SCHEMBL5747866 | 0.80 | TLR8 (0.52) | PARP1ALDH1A1HPGDCYP3A4HSD17B10 | |
| SCHEMBL5747159 | 0.80 | TLR8 (0.52) | PARP1ALDH1A1HPGDCYP3A4HSD17B10 | |
| SCHEMBL5746387 | 0.80 | TLR8 (0.52) | PARP1ALDH1A1HPGDCYP3A4HSD17B10 | |
| SCHEMBL5749089 | 0.79 | ALDH1A1 (0.59) | PARP1ALDH1A1HPGDCYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |