Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.47 |
| ▸ | HTR2C | P28335 | 4/20 | 0.47 |
| ▸ | HTR2B | P41595 | 4/20 | 0.47 |
| ▸ | HRH2 | P25021 | 3/20 | 0.42 |
| ▸ | CNR1 | P21554 | 4/20 | 0.39 |
| ▸ | CNR2 | P34972 | 4/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | EED | O75530 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5750915 | 0.89 | HTR2A (0.46) | HTR2AHTR2CHTR2BHRH2CNR1 | |
| SCHEMBL4054294 | 0.89 | HTR2A (0.49) | HTR2AHTR2CHTR2BHRH2OPRM1 | |
| SCHEMBL5749305 | 0.83 | HTR2A (0.46) | HTR2AHTR2CHTR2BHRH2ELANE | |
| SCHEMBL5751422 | 0.82 | HRH2 (0.46) | HTR2AHTR2CHTR2BHRH2CNR1 | |
| SCHEMBL4054792 | 0.80 | HTR2A (0.47) | HTR2AHTR2CHTR2BHRH2OPRM1 | |
| SCHEMBL4054343 | 0.79 | HTR2A (0.65) | HTR2AHTR2CHTR2BHRH2ELANE | |
| SCHEMBL6226186 | 0.77 | GPR119 (0.43) | HTR2AHTR2CHTR2BHRH2KMT2A | |
| SCHEMBL4058326 | 0.77 | HTR2A (0.43) | HTR2AHTR2CHTR2BHRH2CNR1 | |
| SCHEMBL4053180 | 0.77 | HTR2A (0.62) | HTR2AHTR2CHTR2BHRH2KMT2A | |
| SCHEMBL4060001 | 0.76 | HTR2A (0.76) | HTR2AHTR2CHTR2BHRH2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497292-B1 | AZAINDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | ALMIRALL PRODESFARMA SA (ES) | 2006-06-14 | — | — | EP | claimed |