SCHEMBL5750554

SCHEMBL5750554

CCOC(=O)C(Cc1cccc(OC(F)(F)C(F)F)c1)C(O)c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5753416 0.92 CETP (0.47) CETP
SCHEMBL5751678 0.89 CETP (0.57) CETP
SCHEMBL5752446 0.89 CETP (0.50) CETP
SCHEMBL5752277 0.85 CETP (0.46) CETP
SCHEMBL5750254 0.84 ALDH1A1 (0.39) CETP
SCHEMBL5751981 0.82 ALDH1A1 (0.39) CETP
SCHEMBL5749151 0.82 CETP (0.58) CETP
SCHEMBL5753775 0.81 MAPK14 (0.47) CETP
SCHEMBL5749823 0.81 MEN1 (0.48)
SCHEMBL5751388 0.80 CETP (0.52) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1697337-A2 ORNITHINE DERIVATIVES AS PROSTAGLANDIN-E2-AGONISTS OR ANTAGONISTS Astellas Pharma Inc. (JP) 2006-09-06 EP disclosed
WO-2005061475-A2 ORNITHINE DERIVATIVES AS PROSTAGLANDIN E2 AGONISTS OR ANTAGONISTS ASTELLAS PHARMA INC. (JP) 2005-07-07 WO disclosed