⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17870996 | 1.00 | — | — | |
| SCHEMBL1355721 | 0.97 | — | — | |
| SCHEMBL2538895 | 0.97 | — | — | |
| SCHEMBL575223 | 0.90 | — | — | |
| Methylamine SCHEMBL27878456 | 0.82 | — | — | |
| SCHEMBL1148178 | 0.75 | — | — | |
| SCHEMBL9745363 | 0.71 | — | — | |
| SCHEMBL11278954 | 0.71 | — | — | |
| SCHEMBL11289895 | 0.69 | ALDH1A1 (0.31) | — | |
| SCHEMBL11289901 | 0.69 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1016 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611856-B | Piperidine derivative and pharmaceutical composition, preparation method and application thereof | 宜昌人福药业有限责任公司 | 2024-07-05 | — | — | CN | claimed |
| CN-117983302-A | Catalyst containing ferrocene PNP ligand for ethylene selective tetramerization and preparation method and application thereof | 华东理工大学 | 2024-05-07 | — | — | CN | claimed |
| EP-4345096-A1 | PIPERIDINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF | Yichang Humanwell Pharmaceutical Co., Ltd. (CN) | 2024-04-03 | — | — | EP | claimed |
| CN-117642389-A | Piperidine derivative and pharmaceutical composition, preparation method and application thereof | 宜昌人福药业有限责任公司 | 2024-03-01 | — | — | CN | claimed |
| CN-117642402-A | Spiropiperidine ring derivative and pharmaceutical composition, preparation method and application thereof | 宜昌人福药业有限责任公司 | 2024-03-01 | — | — | CN | claimed |
| WO-2023284834-A1 | PIPERIDINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF | 宜昌人福药业有限责任公司 | 2023-01-19 | — | — | WO | claimed |
| WO-2023284833-A1 | SPIROCYCLIC PIPERIDINE DERIVATIVE, PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF | 宜昌人福药业有限责任公司 | 2023-01-19 | — | — | WO | claimed |
| CN-115611856-A | Piperidine derivative and pharmaceutical composition, preparation method and application thereof | 宜昌人福药业有限责任公司 | 2023-01-17 | — | — | CN | claimed |
| CN-105308054-B | substituted thiazole and pyrimidine | 拜耳制药股份公司 | 2017-11-21 | — | — | CN | claimed |
| EP-2794573-B1 | NOVEL INSECTICIDAL AROMATIC AMIDES | BAYER IP GMBH (DE) | 2017-08-30 | — | — | EP | claimed |
| US-20050038212-A1 | Ligands, complexes, and their use for the polymerization of olefins | BASF AKTIENGESELLSCHAFT (DE) | 2005-02-17 | — | — | US | claimed |
| CN-1578773-A | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS INC (US) | 2005-02-09 | — | — | CN | claimed |
| EP-0405537-B1 | N-substituted cycloalkyl and polycycloalkyl alpha-substituted Trp-Phe- and phenethylamine derivatives | WARNER LAMBERT CO (US) | 2004-09-08 | — | — | EP | claimed |
| US-5580896-A | Treatment of pain and colorectal cancer with dipeptoids of α-substituted Trp-Phe derivatives | WARNER-LAMBERT COMPANY (US) | 1996-12-03 | — | — | US | claimed |
| US-5278316-A | Indoles | WARNER-LAMBERT COMPANY (US) | 1994-01-11 | — | — | US | claimed |
| EP-0479910-A1 | N-SUBSTITUTED CYCLOALKYL AND POLYCYCLOALKYL ALPHA-SUBSTITUTED Trp-Phe- AND PHENETHYLAMINE DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1992-04-15 | — | — | EP | claimed |
| CN-1049165-A | The cycloalkyl that N-replaces and the tryptophane-phenylalanine of multi-ring alkyl alpha-substitution-and phenylethylamine derivative | WARNER LAMBERT CO (US) | 1991-02-13 | — | — | CN | claimed |
| WO-1991000274-A1 | N-SUBSTITUTED CYCLOALKYL AND POLYCYCLOALKYL ALPHA-SUBSTITUTED TRP-PHE- AND PHENETHYLAMINE DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1991-01-10 | — | — | WO | claimed |
| EP-0405537-A1 | N-substituted cycloalkyl and polycycloalkyl alpha-substituted Trp-Phe- and phenethylamine derivatives | WARNER-LAMBERT COMPANY (US) | 1991-01-02 | — | — | EP | claimed |
| US-4110319-A | NATURAL RUBBER OR DIENE POLYMERS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-08-29 | — | — | US | claimed |