SCHEMBL5751126

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5751121	1.00	AOC3 (0.45)	AOC3PTGS1PTGS2ALDH1A1UGCG
	SCHEMBL5750465	0.85	AOC3 (0.45)	AOC3PTGS1PTGS2ALDH1A1UGCG
	SCHEMBL5747091	0.84	AOC3 (0.44)	AOC3PTGS1PTGS2ALDH1A1UGCG
	SCHEMBL5659963	0.80	AOC3 (0.46)	AOC3PTGS1PTGS2ALDH1A1UGCG
	SCHEMBL5659968	0.80	AOC3 (0.46)	AOC3PTGS1PTGS2ALDH1A1UGCG
	SCHEMBL3780503	0.77	AOC3 (0.51)	AOC3PTGS1PTGS2ALDH1A1UGCG
	SCHEMBL10729794	0.76	KMT2A (0.64)	ALDH1A1HTR1AMAPT
	SCHEMBL22478570	0.72	PTGS1 (0.58)	AOC3PTGS1PTGS2ALDH1A1KDM4E
	SCHEMBL10728130	0.71	HTR1A (0.49)	AOC3ALDH1A1HTR1AKDM4EMAPT
	SCHEMBL10728375	0.71	IGF1R (0.62)	AOC3ALDH1A1HTR1AKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.