Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.43 |
| ▸ | CTSK | P43235 | 4/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.41 |
| ▸ | CETP | P11597 | 9/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5751133 | 0.90 | KLK5 (0.40) | CTSSCTSKKLK5CETPLMNA | |
| SCHEMBL5752754 | 0.90 | KLK5 (0.42) | CTSSCTSKKLK5CETPLMNA | |
| SCHEMBL5750069 | 0.89 | CETP (0.41) | CETPLMNAPOLBBACE1 | |
| SCHEMBL5751942 | 0.87 | KLK5 (0.39) | CTSSCTSKKLK5CETPLMNA | |
| SCHEMBL5752574 | 0.86 | KLK1 (0.44) | CETP | |
| SCHEMBL5755604 | 0.86 | KLK5 (0.44) | CTSSCTSKKLK5LMNACTSB | |
| SCHEMBL5752054 | 0.85 | CTSS (0.44) | CTSSCTSKKLK5LMNACTSB | |
| SCHEMBL5749779 | 0.80 | CETP (0.40) | CETPLMNAPOLBBACE1 | |
| SCHEMBL1900658 | 0.79 | CETP (0.39) | CETPLMNAPOLBBACE1 | |
| SCHEMBL5754542 | 0.79 | CETP (0.39) | CETPLMNAPOLBBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6982348-B2 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-01-03 | — | — | US | disclosed |
| US-20040127574-A1 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127574-A1 | Aminoethanol derivatives | CETP, LCAT, MTTP | CTSS 3800/4885CTSK 4401/4885KLK5 3906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.