Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5746900 | 0.93 | HTT (0.40) | HTTCA1CA2CLK1DYRK1A | |
| SCHEMBL818940 | 0.80 | HTT (0.52) | HTTCA1CA2CLK1DYRK1A | |
| SCHEMBL18322219 | 0.78 | HTT (0.53) | HTTCA1CA2CLK1DYRK1A | |
| SCHEMBL644339 | 0.77 | CA1 (0.40) | HTTCA1CA2DYRK1AKDM4E | |
| SCHEMBL31050903 | 0.76 | CA1 (0.52) | HTTCA1CA2CLK1DYRK1A | |
| SCHEMBL32172 | 0.76 | CA1 (0.52) | HTTCA1CA2CLK1DYRK1A | |
| SCHEMBL31050902 | 0.76 | CA1 (0.52) | HTTCA1CA2CLK1DYRK1A | |
| SCHEMBL2701955 | 0.75 | CYP1A2 (0.52) | ALDH1A1 | |
| SCHEMBL30858824 | 0.74 | CA1 (0.50) | HTTCA1CA2CLK1DYRK1A | |
| SCHEMBL28488846 | 0.74 | CA1 (0.50) | HTTCA1CA2CLK1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |