Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3687586 | 0.81 | FFAR1 (0.43) | TDP1ABCB1CYP4F2CYP4A11FFAR1 | |
| SCHEMBL5751152 | 0.80 | CCNC (0.45) | TDP1ABCB1CYP4F2CYP4A11ALOX5 | |
| SCHEMBL3688885 | 0.79 | MAPK1 (0.48) | TDP1ABCB1CYP4F2CYP4A11MAPK1 | |
| Ethyl 3-Phenylpropanoate SCHEMBL304816 | 0.77 | TDP1 (0.75) | TDP1ABCB1CYP4F2CYP4A11ALOX5 | |
| SCHEMBL6379462 | 0.77 | CYP4F2 (0.45) | TDP1ABCB1CYP4F2CYP4A11ALOX5 | |
| SCHEMBL3687493 | 0.76 | CYP4F2 (0.48) | CYP4F2CYP4A11THRATHRB | |
| SCHEMBL3685248 | 0.76 | THRA (0.49) | TDP1CYP4F2CYP4A11THRATHRB | |
| SCHEMBL3692367 | 0.76 | MAOB (0.46) | CYP4F2CYP4A11FFAR1THRATHRB | |
| Ethyl 3-Phenylpropanoate SCHEMBL7440447 | 0.75 | TDP1 (0.72) | TDP1ABCB1CYP4F2CYP4A11ALOX5 | |
| SCHEMBL25760634 | 0.74 | CYP4F2 (0.46) | ABCB1CYP4F2CYP4A11THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660427-A4 | SUBSTITUTED ARYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2006-12-20 | — | — | EP | disclosed |
| EP-1660427-A1 | SUBSTITUTED ARYLALKANOIC ACID DERIVATIVE AND USE THEREOF | Asahi Kasei Pharma Corporation (JP) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005016862-A1 | SUBSTITUTED ARYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORPORATION (JP) | 2005-02-24 | — | — | WO | disclosed |