SCHEMBL5751852

SCHEMBL5751852

COc1cc(O)c(C(=O)c2ccc(N)cc2)cc1S(=O)(=O)O

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.76
LMNA P02545 4/20 0.76
ALDH1A1 P00352 4/20 0.76
KMT2A Q03164 3/20 0.76
KDM4E B2RXH2 2/20 0.51
CYP3A4 P08684 2/20 0.51
HPGD P15428 2/20 0.51
RECQL P46063 2/20 0.51
HSD17B10 Q99714 2/20 0.51
SLC22A6 Q4U2R8 1/20 0.44
SLC22A8 Q8TCC7 1/20 0.44
STS P08842 1/20 0.43
PTPN1 P18031 1/20 0.42
PKM P14618 1/20 0.42
HTT P42858 3/20 0.41
NPSR1 Q6W5P4 1/20 0.41
RAB9A P51151 2/20 0.41
MEN1 O00255 1/20 0.41
NPC1 O15118 2/20 0.41
CA1 P00915 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4660285 0.88 MAPT (0.78) MAPTLMNAALDH1A1KMT2AKDM4E
SCHEMBL9645273 0.88 MAPT (0.78) MAPTLMNAALDH1A1KMT2AKDM4E
SCHEMBL4661529 0.87 MAPT (0.76) MAPTLMNAALDH1A1KMT2AKDM4E
SCHEMBL4660275 0.87 MAPT (0.76) MAPTLMNAALDH1A1KMT2AKDM4E
Sulisobenzone SCHEMBL16330 0.86 LMNA (1.00) MAPTLMNAALDH1A1KMT2AKDM4E
Sulisobenzone SCHEMBL29360128 0.86 LMNA (1.00) MAPTLMNAALDH1A1KMT2AKDM4E
Sulisobenzone SCHEMBL167868 0.86 LMNA (1.00) MAPTLMNAALDH1A1KMT2AKDM4E
Sulisobenzone SCHEMBL9474717 0.86 LMNA (1.00) MAPTLMNAALDH1A1KMT2AKDM4E
Sulisobenzone SCHEMBL8164501 0.86 LMNA (0.71) MAPTLMNAALDH1A1KMT2AKDM4E
Sulisobenzone SCHEMBL489977 0.85 LMNA (0.97) MAPTLMNAALDH1A1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717140-B1 Method for the treatment of textile fibres CIBA SC HOLDING AG (CH) 2006-08-09 EP disclosed
US-5700394-A APPLYING TO FIBER AN ULTRAVIOLET LIGHT ABSORBING DIAMINOHALO-1,3,5-TRIAZINE DERIVATIVE REACTIVE DYE FOR IMPROVED TEAR STRENGTH; SUNSCREEN AGENTS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1997-12-23 US disclosed
EP-0717140-A2 Method for the treatment of textile fibres CIBA-GEIGY AG (CH) 1996-06-19 EP disclosed
US-5500024-A DISCOLORATION INHIBITION; INTRAOCULAR AND CONTACT LENSES; BONDED TO POLYMER CIBA-GEIGY CORPORATION (US) 1996-03-19 US disclosed
US-5399692-A Ultraviolet absorbing benzophenone sulfonic acid derivatives CIBA-GEIGY CORPORATION (US) 1995-03-21 US disclosed
US-5298033-A An absorber bonded to lens formed of hydroxyethyl methacrylate CIBA-GEIGY CORPORATION (US) 1994-03-29 US disclosed