Butane

Butane

SCHEMBL5751985

CCCC.O=C(O)C(Br)C(=O)O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.46
PPARD Q03181 1/20 0.46
ZDHHC20 Q5W0Z9 1/20 0.46
ZDHHC2 Q9UIJ5 1/20 0.46
HDAC1 Q13547 2/20 0.46
HDAC2 Q92769 2/20 0.46
CHRM1 P11229 1/20 0.46
AKR1A1 P14550 1/20 0.46
CHRM3 P20309 1/20 0.46
HTR2A P28223 1/20 0.46
HTR2C P28335 1/20 0.46
ADRA1A P35348 1/20 0.46
HRH1 P35367 1/20 0.46
DRD3 P35462 1/20 0.46
SLC6A3 Q01959 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ALDH1A1 P00352 3/20 0.44
THRB P10828 1/20 0.44
RECQL P46063 1/20 0.44
CYP2C19 P33261 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5610833 0.83
SCHEMBL9400797 0.79 ALDH1A1 (0.57) LCKPPARDZDHHC20ZDHHC2TDP1
SCHEMBL27351876 0.78 HDAC1 (0.43) LCKPPARDZDHHC20ZDHHC2HDAC1
Butane SCHEMBL4877550 0.77 LCK (0.67) LCKPPARDZDHHC20ZDHHC2HDAC1
SCHEMBL4895644 0.77
Acetic Acid SCHEMBL28009021 0.75 HDAC1 (0.40) LCKPPARDZDHHC20ZDHHC2HDAC1
SCHEMBL3218141 0.73 ALDH1A1 (0.43) LCKPPARDZDHHC20ZDHHC2ALDH1A1
Butane SCHEMBL21633593 0.71 FFAR3 (0.54) PPARDHDAC1HDAC2CHRM1AKR1A1
Butane SCHEMBL1165212 0.71 FFAR3 (0.54) PPARDHDAC1HDAC2CHRM1AKR1A1
Butane SCHEMBL1716773 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3431464-A2 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF Senomyx Inc. (US) 2019-01-23 EP disclosed
EP-1659881-A2 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF Senomyx Inc. (US) 2006-05-31 EP disclosed
WO-2005041684-A2 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF SENOMYX INC. (US) 2005-05-12 WO disclosed