⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Chloropyridine SCHEMBL11389784 | 0.97 | — | — | |
| 2-Chloropyridine SCHEMBL10690176 | 0.97 | TDP1 (1.00) | — | |
| 2-Chloropyridine SCHEMBL28283275 | 0.97 | TDP1 (1.00) | — | |
| 2-Chloropyridine SCHEMBL16637 | 0.97 | — | — | |
| 2-Chloropyridine SCHEMBL29402311 | 0.97 | — | — | |
| 2-Chloropyridine SCHEMBL457535 | 0.94 | — | — | |
| 2-Chloropyridine SCHEMBL1935752 | 0.94 | — | — | |
| 2-Chloropyridine SCHEMBL11437985 | 0.94 | — | — | |
| 2-Chloropyridine SCHEMBL21640063 | 0.94 | — | — | |
| 2-Chloropyridine SCHEMBL932532 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108484492-A | Niacinamide synthesizes the technical study of 2,3,6- trichloropyridines | 安徽国星生物化学有限公司 | 2018-09-04 | — | — | CN | disclosed |
| CN-107815702-A | A kind of preparation method of 2,3,5 trichloropyridine | 浙江工业大学 | 2018-03-20 | — | — | CN | disclosed |
| CN-102964294-A | Pyridyl inhibitors of hedgehog signalling | GENENTECH INC | 2013-03-13 | — | — | CN | disclosed |
| CN-102083822-A | Pyridyl inhibitors of HEDGEHOG signalling | GENENTECH INC | 2011-06-01 | — | — | CN | disclosed |
| CN-101772508-A | Bipyridine compound, transition metal complex, and method for production of conjugated aromatic compound using the transition metal complex | SUMITOMO CHEMICAL CO | 2010-07-07 | — | — | CN | disclosed |
| CN-101072755-A | Pyridyl inhibitors of Hedgehog signaling | GENENTECH INC (US) | 2007-11-14 | — | — | CN | disclosed |
| EP-1387839-B1 | PROCESS FOR THE PRODUCTION OF QUINAZOLINES | PFIZER LTD (GB) | 2006-03-08 | — | — | EP | disclosed |
| EP-1430068-A1 | 6-O-CARBAMATE-11,12-LACTO-KETOLIDE ANTIMICROBIALS | Ortho-Mcneil Pharmaceutical, Inc. (US) | 2004-06-23 | — | — | EP | disclosed |
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | disclosed |
| US-6734303-B2 | THERAPY FOR BENIGN PROSTATIC HYPERPLASIA | PFIZER INC. | 2004-05-11 | — | — | US | disclosed |
| US-6713455-B2 | A BICYCLIC HETEROAROMATIC COMPOUND CONTAINING TWO KETO, TWO ESTER, A CARBAMATE GROUPS AND A METHYL, HYDROXY AND AMINE SUBSTITUTED OXYPYRAN RING; USEFUL ANTIBACTERIAL AGENT FOR TREATING PNEUMONIA, SKIN, SOFT TISSUE AND BONE INFECTIONS | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2004-03-30 | — | — | US | disclosed |
| EP-1387839-A1 | PROCESS FOR THE PRODUCTION OF QUINAZOLINES | Pfizer Limited (GB) | 2004-02-11 | — | — | EP | disclosed |
| US-20030125267-A1 | 6-O-carbamate-11,12-lacto-ketolide antimicrobials | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2003-07-03 | — | — | US | disclosed |
| WO-2003024986-A1 | 6-O-CARBAMATE-11,12-LACTO-KETOLIDE ANTIMICROBIALS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2003-03-27 | — | — | WO | disclosed |
| US-20030004339-A1 | Process for the production of quinazolines | PFIZER INC. | 2003-01-02 | — | — | US | disclosed |
| WO-2002094815-A1 | PROCESS FOR THE PRODUCTION OF QUINAZOLINES | PFIZER LIMITED (GB) | 2002-11-28 | — | — | WO | disclosed |
| CN-1073110-C | Process for the preparation of biphenyl derivatives | AMERICAN HOME PROD (US) | 2001-10-17 | — | — | CN | disclosed |
| CN-1192214-A | Process for the preparation of biphenyl derivatives | AMERICAN HOME PROD (US) | 1998-09-02 | — | — | CN | disclosed |