Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA7 | P43166 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5137955 | 0.83 | TDP1 (0.48) | CA1CA12CA9LMNAMAPT | |
| SCHEMBL20340201 | 0.83 | TDP1 (0.48) | CA1CA12CA9LMNAMAPT | |
| SCHEMBL3799471 | 0.82 | CA1 (0.45) | PDPK1CA1CA2CA12CA7 | |
| SCHEMBL20340037 | 0.82 | CA1 (0.45) | PDPK1CA1CA2CA12CA7 | |
| SCHEMBL27781150 | 0.82 | CA1 (0.45) | PDPK1CA1CA2CA12CA7 | |
| SCHEMBL5808414 | 0.82 | CA1 (0.45) | PDPK1CA1CA2CA12CA7 | |
| SCHEMBL16816938 | 0.74 | AKR1B1 (0.40) | PDPK1LMNAMAPTHTTHSD17B10 | |
| SCHEMBL28970873 | 0.72 | CA1 (0.52) | PDPK1CA1CA2CA12CA7 | |
| SCHEMBL27685854 | 0.72 | PDPK1 (0.87) | PDPK1CA1CA2CA12CA7 | |
| SCHEMBL1223467 | 0.71 | CA1 (0.50) | PDPK1CA1CA2CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018126183-A2 | HER3 PEPTIDES FOR IMAGING AND RADIOTHERAPY | THE GENERAL HOSPITAL CORPORATION (US) | 2018-07-05 | — | — | WO | disclosed |
| EP-2794645-A1 | CATIONIC PEPTIDES AND USE OF SUCH PEPTIDES FOR INHIBITING EXOTOXIN PRODUCTION | Regents of the University of Minnesota (US) | 2014-10-29 | — | — | EP | disclosed |
| WO-2013096823-A1 | CATIONIC PEPTIDES AND USE OF SUCH PEPTIDES FOR INHIBITING EXOTOXIN PRODUCTION | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2013-06-27 | — | — | WO | disclosed |
| EP-1658264-A2 | METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | Neurochem (International) Limited (CH) | 2006-05-24 | — | — | EP | disclosed |
| EP-1542709-A2 | PEPTIDE AGGREGATES | EPIX Pharmaceuticals, Inc. (US) | 2005-06-22 | — | — | EP | disclosed |
| WO-2004113277-A2 | METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2004-12-29 | — | — | WO | disclosed |
| WO-2004013161-A2 | PEPTIDE AGGREGATES | EPIX PHARMACEUTICALS, INC. (US) | 2004-02-12 | — | — | WO | disclosed |