Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 4/20 | 0.47 |
| ▸ | CES2 | O00748 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5137955 | 1.00 | TDP1 (0.48) | TDP1L3MBTL1ATMGAAHSP90AA1 | |
| SCHEMBL5752186 | 0.83 | PDPK1 (0.50) | RAB9ACES2LMNAMEN1KMT2A | |
| SCHEMBL15984954 | 0.81 | TDP1 (0.47) | TDP1L3MBTL1ATMGAAHSP90AA1 | |
| SCHEMBL17785195 | 0.81 | TDP1 (0.47) | TDP1L3MBTL1ATMGAAHSP90AA1 | |
| SCHEMBL851629 | 0.81 | TDP1 (0.47) | TDP1L3MBTL1ATMGAAHSP90AA1 | |
| SCHEMBL7440566 | 0.81 | TDP1 (0.47) | TDP1L3MBTL1ATMGAAHSP90AA1 | |
| SCHEMBL5555205 | 0.81 | TDP1 (0.47) | TDP1L3MBTL1ATMGAAHSP90AA1 | |
| SCHEMBL13245918 | 0.80 | KMT2A (0.50) | TDP1L3MBTL1ATMGAAHSP90AA1 | |
| SCHEMBL10666925 | 0.79 | ATM (0.49) | TDP1L3MBTL1ATMGAAHSP90AA1 | |
| SCHEMBL11404130 | 0.79 | ATM (0.49) | TDP1L3MBTL1ATMGAAHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018126183-A2 | HER3 PEPTIDES FOR IMAGING AND RADIOTHERAPY | THE GENERAL HOSPITAL CORPORATION (US) | 2018-07-05 | — | — | WO | disclosed |