Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 9/20 | 0.55 |
| ▸ | CTSK | P43235 | 8/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.41 |
| ▸ | FPR1 | P21462 | 4/20 | 0.40 |
| ▸ | FPR2 | P25090 | 4/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21144822 | 0.83 | CTSS (0.49) | CTSSCTSKCTSLCTSBKLK5 | |
| SCHEMBL18930599 | 0.83 | CTSS (0.49) | CTSSCTSKCTSLCTSBKLK5 | |
| SCHEMBL25383602 | 0.82 | CTSS (0.61) | CTSSCTSKCTSLCTSBKLK5 | |
| SCHEMBL25383608 | 0.82 | CTSS (0.61) | CTSSCTSKCTSLCTSBKLK5 | |
| SCHEMBL20028143 | 0.82 | CTSS (0.61) | CTSSCTSKCTSLCTSBKLK5 | |
| SCHEMBL5945647 | 0.80 | KLK5 (0.48) | CTSSCTSKCTSLCTSBKLK5 | |
| SCHEMBL21170204 | 0.79 | PSEN1 (0.51) | CTSSCTSKCTSLCTSBKLK5 | |
| SCHEMBL18930230 | 0.79 | PSEN1 (0.51) | CTSSCTSKCTSLCTSBKLK5 | |
| SCHEMBL20028141 | 0.77 | CTSS (0.55) | CTSSCTSKCTSLCTSBKLK5 | |
| SCHEMBL22506384 | 0.77 | CTSS (0.44) | CTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6982348-B2 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-01-03 | — | — | US | disclosed |
| US-20040127574-A1 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-07-01 | — | — | US | disclosed |
| EP-1362846-A1 | AMINOETHANOL DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2003-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127574-A1 | Aminoethanol derivatives | CETP, LCAT, MTTP | CTSS 3800/4885CTSK 4401/4885CTSL 2240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.