Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4678687 | 0.93 | CNR1 (0.53) | CNR1CNR2 | |
| SCHEMBL4680341 | 0.89 | CNR1 (0.49) | CNR1CNR2 | |
| SCHEMBL4680688 | 0.89 | CNR1 (0.49) | CNR1CNR2 | |
| SCHEMBL4680579 | 0.83 | CNR1 (0.53) | CNR1CNR2 | |
| SCHEMBL4680303 | 0.82 | CNR1 (0.49) | CNR1CNR2 | |
| SCHEMBL4680846 | 0.82 | LIPE (0.48) | CNR1CNR2 | |
| SCHEMBL4681746 | 0.78 | CNR1 (0.58) | CNR1CNR2 | |
| SCHEMBL4680663 | 0.78 | LIPE (0.44) | CNR1CNR2 | |
| SCHEMBL4684134 | 0.78 | LIPE (0.44) | CNR1CNR2 | |
| SCHEMBL4681525 | 0.78 | CNR1 (0.61) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638953-A1 | 3-SUBSTITUTED 5,6-DIARYL-PYRAZINE-2-CARBOXAMIDE AND -2-SULFONAMIDE DERIVATIVES AS CB1 MODULATORS | AstraZeneca AB (SE) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004111034-A1 | 3-SUBSTITUTED 5,6-DIARYL-PYRAZINE-2-CARBOXAMIDE AND -2-SULFONAMIDE DERIVATIVES AS CB1 MODULATORS | ASTRAZENECA AB (SE) | 2004-12-23 | — | — | WO | disclosed |