Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 6/20 | 0.56 |
| ▸ | CDK8 | P49336 | 6/20 | 0.56 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5752674 | 0.85 | CCNC (0.51) | CCNCCDK8ADRA2AADRA2BADRA2C | |
| SCHEMBL5751149 | 0.80 | PDE3B (0.44) | CCNCCDK8P2RY12ADRA2AADRA2B | |
| SCHEMBL6552271 | 0.77 | TTR (0.64) | CCNCCDK8P2RY12TTRDPP4 | |
| SCHEMBL31408755 | 0.77 | TTR (0.64) | CCNCCDK8P2RY12TTRDPP4 | |
| SCHEMBL4866988 | 0.77 | TTR (0.64) | CCNCCDK8P2RY12TTRDPP4 | |
| SCHEMBL2906674 | 0.77 | TTR (0.64) | CCNCCDK8P2RY12TTRDPP4 | |
| SCHEMBL8541449 | 0.76 | CCNC (0.48) | CCNCCDK8CDK19P2RY12TTR | |
| SCHEMBL3683531 | 0.76 | CCNC (0.57) | CCNCCDK8CDK19P2RY12TTR | |
| SCHEMBL3683530 | 0.76 | CCNC (0.57) | CCNCCDK8CDK19P2RY12TTR | |
| SCHEMBL3881194 | 0.73 | CCNC (0.49) | CCNCCDK8CDK19TTRDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660427-A4 | SUBSTITUTED ARYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2006-12-20 | — | — | EP | disclosed |
| EP-1660427-A1 | SUBSTITUTED ARYLALKANOIC ACID DERIVATIVE AND USE THEREOF | Asahi Kasei Pharma Corporation (JP) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005016862-A1 | SUBSTITUTED ARYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORPORATION (JP) | 2005-02-24 | — | — | WO | disclosed |