Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 4/20 | 0.51 |
| ▸ | CDK8 | P49336 | 4/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.41 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5752989 | 0.85 | CCNC (0.56) | CCNCCDK8ADRA2AADRA2BADRA2C | |
| SCHEMBL11833573 | 0.76 | KDM4E (0.59) | PIM2ESR1KDM4EALDH1A1 | |
| SCHEMBL11833578 | 0.76 | KDM4E (0.59) | PIM2ESR1KDM4EALDH1A1 | |
| SCHEMBL5748903 | 0.76 | CCNC (0.51) | CCNCCDK8ADRA2AADRA2BADRA2C | |
| SCHEMBL5914832 | 0.74 | ADRA2A (0.44) | ADRA2AADRA2BADRA2CCSNK1A1TYRO3 | |
| SCHEMBL5914848 | 0.73 | NISCH (0.41) | ADRA2AADRA2BADRA2CCSNK1A1TYRO3 | |
| SCHEMBL17403503 | 0.73 | HDAC2 (0.58) | CCNCCDK8BACE1RAB9AAKR1C4 | |
| SCHEMBL6552210 | 0.73 | RELA (0.62) | BACE1RAB9ACYP1A1CYP1A2CYP3A4 | |
| SCHEMBL78426 | 0.73 | RELA (0.62) | BACE1RAB9ACYP1A1CYP1A2CYP3A4 | |
| SCHEMBL78427 | 0.73 | RELA (0.62) | BACE1RAB9ACYP1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660427-A4 | SUBSTITUTED ARYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2006-12-20 | — | — | EP | disclosed |
| EP-1660427-A1 | SUBSTITUTED ARYLALKANOIC ACID DERIVATIVE AND USE THEREOF | Asahi Kasei Pharma Corporation (JP) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005016862-A1 | SUBSTITUTED ARYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORPORATION (JP) | 2005-02-24 | — | — | WO | disclosed |