Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
| ▸ | SLC2A1 | P11166 | 8/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983819 | 1.00 | KCNH2 (0.57) | KCNH2SLC2A1CYP2D6KDM4EALDH1A1 | |
| SCHEMBL6988402 | 0.85 | CYP2D6 (0.44) | KCNH2SLC2A1CYP2D6KDM4EALDH1A1 | |
| SCHEMBL13356412 | 0.84 | SLC2A1 (0.59) | KCNH2SLC2A1CYP2D6KDM4EALDH1A1 | |
| SCHEMBL13356470 | 0.84 | SLC2A1 (0.59) | KCNH2SLC2A1CYP2D6KDM4EALDH1A1 | |
| SCHEMBL5253301 | 0.84 | KCNH2 (0.61) | KCNH2SLC2A1CYP2D6KDM4EALDH1A1 | |
| SCHEMBL5253304 | 0.84 | KCNH2 (0.61) | KCNH2SLC2A1CYP2D6KDM4EALDH1A1 | |
| SCHEMBL5754730 | 0.82 | SLC2A1 (0.56) | KCNH2SLC2A1CYP2D6KDM4EALDH1A1 | |
| SCHEMBL4269291 | 0.82 | SLC2A1 (0.63) | KCNH2SLC2A1CYP2D6KDM4EALDH1A1 | |
| SCHEMBL5256391 | 0.82 | SLC2A1 (0.63) | KCNH2SLC2A1CYP2D6KDM4EALDH1A1 | |
| SCHEMBL5256396 | 0.82 | SLC2A1 (0.63) | KCNH2SLC2A1CYP2D6KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343765-B1 | QUINOLINES AND NITROGENATED DERIVATIVES THEREOF SUBSTITUTED IN 4-POSITION BY A PIPERAZINE-CONTAINING MOIETY AND THEIR USE AS ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 2006-11-22 | — | — | EP | disclosed |
| US-20040077656-A1 | Quinolines and nitrogenated derivatives thereof substituted in 4-position by a piperazine-containing moiety and their use as antibacterial agents | SMITHKLINE BEECHAM P.L.C. (GB) | 2004-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077656-A1 | Quinolines and nitrogenated derivatives thereof substituted in 4-position by a piperazine-containing moiety and their use as antibacterial agents | NQO2, ASNS, QARS1 | KCNH2 1467/4885SLC2A1 3955/4885CYP2D6 525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.