Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 4/20 | 0.37 |
| ▸ | RXRG | P48443 | 4/20 | 0.37 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3613341 | 0.73 | CXCR5 (0.53) | RXRAALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL5749754 | 0.72 | ALDH1A1 (0.38) | RXRAALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL5753055 | 0.71 | CXCR5 (0.39) | RXRAALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL5753051 | 0.71 | CXCR5 (0.39) | RXRAALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL783869 | 0.70 | CXCR5 (0.56) | RXRAALDH1A1RXRBRXRGCXCR5 | |
| SCHEMBL29493191 | 0.70 | CXCR5 (0.56) | RXRAALDH1A1RXRBRXRGCXCR5 | |
| Phthalic Acid SCHEMBL27608269 | 0.69 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDCXCR5ALOX15 | |
| SCHEMBL5755502 | 0.68 | CXCR5 (0.55) | RXRAALDH1A1RXRBRXRGCXCR5 | |
| SCHEMBL27627344 | 0.68 | ALDH1A1 (0.50) | ALDH1A1HSD17B10KDM4EHPGDMYC | |
| SCHEMBL27536926 | 0.68 | TSHR (0.49) | ALDH1A1HSD17B10KDM4EHPGDMYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6982348-B2 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-01-03 | — | — | US | disclosed |
| US-20040127574-A1 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-07-01 | — | — | US | disclosed |
| EP-1362846-A1 | AMINOETHANOL DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2003-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127574-A1 | Aminoethanol derivatives | CETP, LCAT, MTTP | RXRA 2166/4885ALDH1A1 783/4885HSD17B10 151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.