Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 9/20 | 0.33 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.31 |
| ▸ | BPTF | Q12830 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL262375 | 0.89 | MEN1 (0.48) | MEN1GAAKMT2AALDH1A1KDM4E | |
| SCHEMBL27635209 | 0.83 | KDM4E (0.52) | MEN1GAAKMT2AALDH1A1KDM4E | |
| SCHEMBL1242538 | 0.79 | KMT2A (0.51) | MEN1GAAKMT2AALDH1A1KDM4E | |
| SCHEMBL4103702 | 0.78 | MEN1 (0.53) | MEN1GAAKMT2AALDH1A1KDM4E | |
| SCHEMBL263849 | 0.78 | MEN1 (0.48) | MEN1GAAKMT2AALDH1A1KDM4E | |
| SCHEMBL263848 | 0.78 | MEN1 (0.48) | MEN1GAAKMT2AALDH1A1KDM4E | |
| SCHEMBL27635219 | 0.77 | KDM4E (0.56) | MEN1GAAKMT2AALDH1A1KDM4E | |
| SCHEMBL27656232 | 0.76 | MEN1 (0.54) | MEN1GAAKMT2AALDH1A1KDM4E | |
| SCHEMBL261584 | 0.76 | MEN1 (0.45) | MEN1GAAKMT2AALDH1A1KDM4E | |
| SCHEMBL261583 | 0.76 | MEN1 (0.45) | MEN1GAAKMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1650192-A1 | QUINOLONE DERIVATIVE OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2006-04-26 | — | — | EP | disclosed |