Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 11/20 | 0.55 |
| ▸ | FNTB | P49356 | 11/20 | 0.55 |
| ▸ | HRAS | P01112 | 1/20 | 0.55 |
| ▸ | KRAS | P01116 | 1/20 | 0.55 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GCKR | Q14397 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5755053 | 0.92 | FNTA (0.62) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL5790292 | 0.92 | FNTA (0.62) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL6614317 | 0.88 | FNTA (0.58) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL5787326 | 0.80 | FNTA (0.59) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL5787316 | 0.80 | FNTA (0.59) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL5757506 | 0.79 | FNTA (0.47) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL5757513 | 0.79 | FNTA (0.47) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL7666114 | 0.77 | FNTA (0.47) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL6615549 | 0.77 | FNTA (0.47) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL6630924 | 0.77 | FNTA (0.58) | FNTAFNTBHRASKRASPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140786-B9 | REDUCTIVE ALKYLATION OF SECONDARY AMINES WITH HYDROSILANE | BRISTOL MYERS SQUIBB CO (US) | 2006-05-10 | — | — | EP | claimed |
| EP-1140786-B1 | REDUCTIVE ALKYLATION OF SECONDARY AMINES WITH HYDROSILANE | BRISTOL MYERS SQUIBB CO (US) | 2005-11-30 | — | — | EP | claimed |