Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 11/20 | 0.58 |
| ▸ | FNTB | P49356 | 11/20 | 0.58 |
| ▸ | HRAS | P01112 | 1/20 | 0.58 |
| ▸ | KRAS | P01116 | 1/20 | 0.58 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | GCKR | Q14397 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5790292 | 0.96 | FNTA (0.62) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL5755053 | 0.96 | FNTA (0.62) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL5754745 | 0.88 | FNTA (0.55) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL5757506 | 0.84 | FNTA (0.47) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL5757513 | 0.84 | FNTA (0.47) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL5787326 | 0.83 | FNTA (0.59) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL5787316 | 0.83 | FNTA (0.59) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL6615549 | 0.80 | FNTA (0.47) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL6630924 | 0.80 | FNTA (0.58) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL7666114 | 0.80 | FNTA (0.47) | FNTAFNTBHRASKRASPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892797-A4 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | BRISTOL MYERS SQUIBB CO (US) | 2004-10-20 | — | — | EP | disclosed |
| EP-0892797-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030992-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |