Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 7/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.46 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | WDR5 | P61964 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | ATIC | P31939 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11140543 | 0.98 | SLC22A12 (0.48) | SLC22A12NR4A1NR4A2NR4A3IMPDH2 | |
| Bromide SCHEMBL28912382 | 0.98 | SLC22A12 (0.48) | SLC22A12NR4A1NR4A2NR4A3IMPDH2 | |
| Bromide SCHEMBL11137663 | 0.96 | SLC22A12 (0.47) | SLC22A12NR4A1NR4A2NR4A3IMPDH2 | |
| Bromide SCHEMBL11137660 | 0.96 | SLC22A12 (0.47) | SLC22A12NR4A1NR4A2NR4A3IMPDH2 | |
| SCHEMBL11137666 | 0.93 | SLC22A12 (0.45) | SLC22A12NR4A1NR4A2NR4A3IMPDH2 | |
| SCHEMBL6650616 | 0.90 | SLC22A12 (0.43) | SLC22A12NR4A1NR4A2NR4A3IMPDH2 | |
| SCHEMBL12212891 | 0.89 | NR4A1 (0.52) | SLC22A12NR4A1NR4A2NR4A3STAT3 | |
| SCHEMBL7671048 | 0.83 | IMPDH2 (0.44) | SLC22A12IMPDH2IMPDH1STAT3ALDH1A1 | |
| SCHEMBL13209656 | 0.83 | IMPDH2 (0.49) | SLC22A12IMPDH2IMPDH1STAT3ALDH1A1 | |
| SCHEMBL3220350 | 0.83 | ATM (0.55) | SLC22A12IMPDH2IMPDH1STAT3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4376214-A | Process for the preparation of naphthalene-1,4-dicarboxylic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-03-08 | — | — | US | claimed |
| CN-119591645-A | Isoquinoline-5-formic acid coordinated catalyst, composite catalyst, preparation method and application | 上海元革新材料科技有限公司 | 2025-03-11 | — | — | CN | disclosed |
| CN-115448831-B | Process for preparing 4-acetyl-1-naphthoic acid | 北京元延医药科技股份有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-112778116-A | Preparation method of 1,4-naphthalenedicarboxylic acid | 湖北鸿鑫化工有限公司 | 2021-05-11 | — | — | CN | disclosed |
| US-20110250509-A1 | SECONDARY BATTERY AND ELECTRONIC DEVICE | SONY CORPORATION (JP) | 2011-10-13 | — | — | US | disclosed |
| US-6982348-B2 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-01-03 | — | — | US | disclosed |
| US-20040127574-A1 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-07-01 | — | — | US | disclosed |
| EP-1362846-A1 | AMINOETHANOL DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-6365602-B1 | FOR THERAPY OF DEPRESSION, ANXIETY, ASTHMA, PAIN, INFLAMMATION, URINARY INCONTINENCE AND OTHER DISEASE CONDITIONS | ASTRA ZENECA AB (SE) | 2002-04-02 | — | — | US | disclosed |
| EP-1097137-A1 | N-SUBSTITUTED NAPHTHALENE CARBOXAMIDES AS NEUROKININ-RECEPTOR ANTAGONISTS | AstraZeneca AB (SE) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000002859-A1 | N-SUBSTITUTED NAPHTHALENE CARBOXAMIDES AS NEUROKININ-RECEPTOR ANTAGONISTS | ASTRAZENECA AB (SE) | 2000-01-20 | — | — | WO | disclosed |
| US-4376214-A | Process for the preparation of naphthalene-1,4-dicarboxylic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-03-08 | — | — | US | disclosed |
| US-4376214-A | Process for the preparation of naphthalene-1,4-dicarboxylic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127574-A1 | Aminoethanol derivatives | CETP, LCAT, MTTP | SLC22A12 784/4885NR4A1 595/4885NR4A2 649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.