Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 10/20 | 0.93 |
| ▸ | HTR1A | P08908 | 18/20 | 0.93 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL5760282 | 1.00 | HTR1A (0.93) | HTR1ASLC6A4 | |
| Oxalic Acid SCHEMBL5758948 | 1.00 | HTR1A (0.93) | HTR1ASLC6A4 | |
| Oxalic Acid SCHEMBL5762330 | 1.00 | HTR1A (0.93) | HTR1ASLC6A4 | |
| Oxalic Acid SCHEMBL5758462 | 0.94 | HTR1A (0.93) | HTR1ASLC6A4 | |
| Oxalic Acid SCHEMBL5756446 | 0.94 | HTR1A (0.93) | HTR1ASLC6A4 | |
| Oxalic Acid SCHEMBL5759714 | 0.94 | HTR1A (0.93) | HTR1ASLC6A4 | |
| Oxalic Acid SCHEMBL5756698 | 0.94 | HTR1A (0.93) | HTR1ASLC6A4 | |
| Oxalic Acid SCHEMBL5759360 | 0.94 | HTR1A (0.81) | HTR1ASLC6A4 | |
| Oxalic Acid SCHEMBL5761272 | 0.94 | HTR1A (0.81) | HTR1ASLC6A4 | |
| Oxalic Acid SCHEMBL5760829 | 0.94 | HTR1A (0.81) | HTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242411-B1 | INDOLE DERIVATIVES FOR THE TREATMENT OF DEPRESSION AND ANXIETY | LILLY CO ELI (US) | 2006-03-08 | — | — | EP | disclosed |