Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 19/20 | 0.90 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4868027 | 0.95 | TRPV1 (1.00) | TRPV1 | |
| SCHEMBL4546343 | 0.87 | TRPV1 (0.85) | TRPV1 | |
| SCHEMBL4873167 | 0.87 | TRPV1 (0.81) | TRPV1 | |
| SCHEMBL4869732 | 0.87 | TRPV1 (0.84) | TRPV1 | |
| SCHEMBL4873173 | 0.87 | TRPV1 (0.84) | TRPV1 | |
| SCHEMBL4874196 | 0.87 | TRPV1 (0.84) | TRPV1 | |
| SCHEMBL4869683 | 0.86 | TRPV1 (0.82) | TRPV1 | |
| SCHEMBL10323906 | 0.85 | TRPV1 (0.81) | TRPV1 | |
| SCHEMBL4546333 | 0.84 | TRPV1 (0.82) | TRPV1 | |
| SCHEMBL4866225 | 0.84 | TRPV1 (0.79) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646621-A2 | NOVEL AZAHETEROCYCLIC AMIDES USEFUL FOR TREATING PAIN | Abbott Laboratories (US) | 2006-04-19 | — | — | EP | disclosed |
| WO-2005007642-A2 | NOVEL AZAHETEROCYCLIC AMIDES USEFUL FOR TREATING PAIN | ABBOTT LABORATORIES (US) | 2005-01-27 | — | — | WO | disclosed |