Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | FADS1 | O60427 | 3/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5750810 | 0.85 | KCNN4 (0.33) | KCNN4MDM2ALDH1A1NPSR1FADS1 | |
| SCHEMBL5752903 | 0.83 | KCNN4 (0.35) | KCNN4MDM2FADS1MAOBPTGDR2 | |
| SCHEMBL5754320 | 0.81 | UBE2M (0.35) | KCNN4MDM2FADS1MAOBPTGDR2 | |
| SCHEMBL5751832 | 0.80 | MDM2 (0.35) | KCNN4MDM2FADS1MAOBPTGDR2 | |
| SCHEMBL5751613 | 0.78 | KCNN4 (0.39) | KCNN4MDM2ALDH1A1MAOBPTGDR2 | |
| SCHEMBL5752464 | 0.75 | KCNN4 (0.33) | KCNN4MAOB | |
| SCHEMBL5753523 | 0.75 | HCRTR1 (0.37) | ALDH1A1 | |
| SCHEMBL5754424 | 0.74 | GRM5 (0.35) | MDM2 | |
| SCHEMBL5752417 | 0.74 | KCNN4 (0.33) | KCNN4MAOB | |
| SCHEMBL5749800 | 0.73 | HCRTR1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6982348-B2 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-01-03 | — | — | US | disclosed |
| US-20040127574-A1 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-07-01 | — | — | US | disclosed |
| EP-1362846-A1 | AMINOETHANOL DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2003-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127574-A1 | Aminoethanol derivatives | CETP, LCAT, MTTP | KCNN4 4807/4885MDM2 3868/4885ALDH1A1 783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.