Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 8/20 | 0.54 |
| ▸ | FNTB | P49356 | 8/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5736856 | 0.85 | FNTA (0.73) | FNTAFNTBCYP3A4RORCPGGT1B | |
| SCHEMBL5755627 | 0.85 | FNTA (0.55) | FNTAFNTBCYP3A4RORCPGGT1B | |
| SCHEMBL5755699 | 0.84 | FNTA (0.72) | FNTAFNTBCYP3A4RORC | |
| SCHEMBL5737090 | 0.80 | FNTA (0.59) | FNTAFNTBCYP3A4RORCPGGT1B | |
| SCHEMBL5781801 | 0.77 | FNTA (0.53) | FNTAFNTBCYP3A4RORC | |
| SCHEMBL5071351 | 0.76 | FNTA (0.64) | FNTAFNTBCYP3A4PGGT1B | |
| SCHEMBL6172284 | 0.75 | FNTA (0.61) | FNTAFNTBCYP3A4RORCPGGT1B | |
| SCHEMBL7090978 | 0.74 | FNTA (0.63) | FNTAFNTBCYP3A4RORC | |
| SCHEMBL6167630 | 0.73 | FNTA (0.62) | FNTAFNTBCYP3A4RORCPGGT1B | |
| SCHEMBL6171125 | 0.72 | FNTA (0.55) | FNTAFNTBCYP3A4RORCPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351954-B1 | FARNESYL TRANSFERASE INHIBITING 4-HETEROCYCLYL-QUINOLINE AND QUINAZOLINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2006-05-03 | — | — | EP | claimed |