Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5756642 | 0.88 | SMN1; SMN2 (0.50) | ALDH1A1HPGDTSHRHTTLMNA | |
| SCHEMBL6975596 | 0.85 | SMN1; SMN2 (0.47) | ALDH1A1HPGDTSHRHTTLMNA | |
| SCHEMBL5755066 | 0.84 | SMN1; SMN2 (0.51) | ALDH1A1HPGDTSHRHTTLMNA | |
| SCHEMBL5755974 | 0.84 | ALDH1A1 (0.55) | ALDH1A1HPGDTSHRHTTSMN1; SMN2 | |
| SCHEMBL5754967 | 0.82 | ALDH1A1 (0.53) | ALDH1A1HPGDTSHRHTTSMN1; SMN2 | |
| SCHEMBL5755212 | 0.82 | ALDH1A1 (0.51) | ALDH1A1HPGDTSHRHTTLMNA | |
| SCHEMBL5755034 | 0.81 | ALDH1A1 (0.55) | ALDH1A1HPGDTSHRHTTLMNA | |
| SCHEMBL5755760 | 0.81 | ALDH1A1 (0.51) | ALDH1A1HPGDTSHRHTTSMN1; SMN2 | |
| SCHEMBL5756019 | 0.80 | MAPT (0.53) | ALDH1A1HPGDTSHRHTTLMNA | |
| SCHEMBL5759425 | 0.80 | ALDH1A1 (0.51) | ALDH1A1HPGDTSHRHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208092-B1 | SULFONAMIDE DERIVATIVE AS A MATRIX METALLOPROTEINASE INHIBITOR | SAMSUNG ELECTRONICS CO LTD (KR) | 2006-06-21 | — | — | EP | disclosed |