SCHEMBL5756094

SCHEMBL5756094

NCC(Cc1ccccc1)N1CCCC1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 5/20 0.54
CYP3A4 P08684 5/20 0.54
CYP2D6 P10635 5/20 0.54
CYP2C19 P33261 5/20 0.54
TSHR P16473 1/20 0.54
IDO1 P14902 1/20 0.50
SLC6A2 P23975 4/20 0.49
SLC6A4 P31645 3/20 0.49
SLC6A3 Q01959 3/20 0.49
MC4R P32245 1/20 0.45
OPRM1 P35372 1/20 0.45
OPRD1 P41143 1/20 0.45
OPRK1 P41145 1/20 0.45
CYP2C9 P11712 4/20 0.42
KCNA5 P22460 4/20 0.42
KCNH2 Q12809 4/20 0.42
RAB9A P51151 1/20 0.42
HRH3 Q9Y5N1 1/20 0.42
EPHX1 P07099 1/20 0.42
KCNE1 P15382 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5754933 0.98 CYP3A4 (0.53) CYP1A2CYP3A4CYP2D6CYP2C19TSHR
Hydrochloric Acid SCHEMBL5758457 0.96 CYP3A4 (0.56) CYP1A2CYP3A4CYP2D6CYP2C19TSHR
SCHEMBL7607116 0.84 IDO1 (0.71) CYP2D6IDO1SLC6A2SLC6A4SLC6A3
Hydrochloric Acid SCHEMBL5758790 0.83 DPP4 (0.48) CYP3A4CYP2D6CYP2C19IDO1SLC6A2
SCHEMBL18375354 0.82 OPRK1 (0.49) CYP2C19SLC6A2OPRM1OPRD1OPRK1
SCHEMBL20369820 0.82 OPRK1 (0.49) CYP2C19SLC6A2OPRM1OPRD1OPRK1
SCHEMBL21055084 0.81 IDO1 (0.73) CYP1A2CYP3A4CYP2D6CYP2C19TSHR
SCHEMBL12847327 0.81 CYP3A4 (0.54) CYP1A2CYP3A4CYP2D6CYP2C19TSHR
SCHEMBL4758350 0.81 IDO1 (0.73) CYP1A2CYP3A4CYP2D6CYP2C19TSHR
Hydrochloric Acid SCHEMBL5760504 0.81 KDM4E (0.44) CYP1A2CYP3A4CYP2D6CYP2C19TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015095337-A2 PYRAZOLO[1,5-a]PYRIMIDINECARBOXAMIDE DERIVATIVES FOR TREATING COGNITIVE IMPAIRMENT THE ROCKEFELLER UNIVERSITY (US) 2015-06-25 WO disclosed
EP-1401821-A4 NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS SK CORP (KR) 2006-05-31 EP disclosed
EP-1401821-A1 NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS SK Corporation (KR) 2004-03-31 EP disclosed
WO-2002100848-A1 NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS SK CORPORATION (KR) 2002-12-19 WO disclosed